Protein Alignment daw and bmp2b

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_571435.1
• Gene: bmp2b / 30632
• ZFINID: ZDB-GENE-980526-474
• Length: 411
• Species: Danio rerio
• Alignment Length: 423
• Identity: 101/423 - (23%)
• Similarity: 172/423 - (40%)
• Gaps: 70/423 - (16%)

  Fly   212 LPLGERNITISVKSSAGGCPKCESNRQVE---HITEEQLTHLRIEFVKQQILEK--LRLKESPKV 271
            |.||:    :.:..:.|..|:.:..:..:   |..|...|:...|| :.::|..  |:.|.:|..
Zfish    11 LLLGQ----VLLGGAVGLIPEIDRRKYSDSGRHTPERTDTNFLNEF-ELRLLNMFGLKRKPTPSK 70

  Fly   272 SAVELPKPIFDGMTL-SHPDD-------STKNKELDDYYARTSKKFILLNREEVECNRARDGKSN 328
            ||| :|:.:.|...: |..||       ||..|.::...:|.:......:.|..|...:..||:.
Zfish    71 SAV-VPQYMLDLYYMHSENDDPNIRRPRSTMGKHVERAASRANTIRSFHHEEAFEALSSLKGKTT 134

  Fly   329 PSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLS 393
            ..  |.|.:.....|.. :|.|.|.:|     |.......|||....|.:.||.......||
Zfish   135 QQ--FFFNLTSIPGEEL-ISAAELRIF-----RDQVLGDASTSGFHRINIYEVFRPALAPSK--- 188

  Fly   394 AAKTIAIQSVNVQD---EWMKIDIEWPIKHWI--SGHELSHLIQIT-CGGCDVSDMEE------- 445
            ...|..:.:..|||   .|...|:...:..|.  |.|....|:::. ....:||:..|
Zfish   189 EPLTRLLDTRLVQDSHTRWESFDVGSAVARWARESQHNHGLLVEVLHPKESEVSEEAESNRRKHV 253

  Fly   446 ----IISVDKD----YRPFI-----------VIDMQNRRRKSRQKRSINCSSGMTECCREH-LYI 490
                .:..|:|    .||.:           |:.....:|::|:.:...........||.| ||:
Zfish   254 RVSRSLHADEDSWAQARPLLVTYSHDGQGTAVLHSNREKRQARRGQKPRRKHHQRSNCRRHALYV 318

  Fly   491 SFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVP--CCTA 553
            .|.|:||:.||:.|.||:|::|.|.|.........:::|:.:..::::..:|     :|  ||..
Zfish   319 DFSDVGWNEWIVAPPGYHAFYCHGECPFPLPDHLNSTNHAIVQTLVNSVNSN-----IPKACCIP 378

  Fly   554 KQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            .:.|.:.|:.:|......:|...:||||.||||
Zfish   379 TELSPISLLYLDEYEKVILKNYQDMVVEGCGCR 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	32/104 (31%)
bmp2b	NP_571435.1	TGFb_propeptide	49..276	CDD:459906	55/239 (23%)
		TGF_beta_BMP2_like	311..411	CDD:381638	33/104 (32%)