Protein Alignment daw and Nodal

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001099864.1
• Gene: Nodal / 294503
• RGDID: 1305994
• Length: 354
• Species: Rattus norvegicus
• Alignment Length: 475
• Identity: 95/475 - (20%)
• Similarity: 155/475 - (32%)
• Gaps: 170/475 - (35%)

  Fly   141 HRHVSPPVELPIMYGDAPEESS-----LSSDDHFDDLSPLDFVRNELMAED----QQN------- 189
            |..|:....||:.....|...|     ||.  :.|.|...|.:|: |.|:|    .||
  Rat    19 HPRVATAAALPLWTRGQPSSPSPLAYMLSL--YRDPLPRADIIRS-LQAQDVDVTGQNWTFTFDF 80

  Fly   190 ----QEKDL---DLDLDLDQQPETPIEPELPLGERNITISVKSSAGGCPK-----CESNRQVEHI 242
                ||:||   :|.|.|....::|.:..|       ||.:...|...|:     |.....:|.|
  Rat    81 SFLSQEEDLVWAELRLQLLSPMDSPTKGPL-------TIDIFHQAKPDPEQDPADCLERVWMERI 138

  Fly   243 TEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSK 307
            |   :|..::.|....             :.:|:.||:              :|.|.|  .|..:
  Rat   139 T---VTPSQVTFASDS-------------TVLEVTKPL--------------SKWLKD--PRALE 171

  Fly   308 KFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSA 372
            |.:               .|....|                    |    .|:.|....|.|||
  Rat   172 KQV---------------SSQAGKC--------------------W----HQSHTQPVPVTSTS- 196

  Fly   373 QQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWISGHELSHLIQITCGG 437
                 |..:..::.::.:.|..|..:          | :.:..|..:
  Rat   197 -----VLMLYSNRPQEQRQLGGATLL----------W-EAESSWRAQ------------------ 227

  Fly   438 CDVSDMEEIISVDKDYRPFIVIDMQNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWSNWIL 502
                  |..:||:             |....|::|..:.......|.|....:.|..|||.:||:
  Rat   228 ------EGQLSVE-------------RSGWGRRQRRHHLPDRSQLCRRVKFQVDFNLIGWGSWII 273

  Fly   503 KPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVP--CCTAKQYSSLQLVVMD 565
            .|:.||||.|.|.|.:........::|:.|..:|.....::    ||  ||...:...|.::.:|
  Rat   274 YPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHR----VPSTCCAPVKTKPLSMLYVD 334

  Fly   566 SSNTATVKTLPNMVVESCGC 585
            :.. ..::...:|:||.|||
  Rat   335 NGR-VLLEHHKDMIVEECGC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	27/213 (13%)
		TGF_beta	481..585	CDD:278448	29/105 (28%)
Nodal	NP_001099864.1	TGFb_propeptide	33..169	CDD:279078	38/177 (21%)
		TGFB	254..353	CDD:214556	29/103 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740