Protein Alignment daw and Lefty2

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001007557.1
• Gene: Lefty2 / 289316
• RGDID: 1359679
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 409
• Identity: 86/409 - (21%)
• Similarity: 146/409 - (35%)
• Gaps: 142/409 - (34%)

  Fly   242 ITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTL--------------SHPDDS 292
            :||||        |...:|::|:|.::|.:..|::     :||.:              ||.|.|
  Rat    22 VTEEQ--------VLSSLLKQLQLSQAPVLDRVDV-----EGMAIPTHVSSQYVALLQGSHADRS 73

  Fly   293 TKNKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKN 357
             :.|.....:...:.:|::              ....|....|.::.......::..|:|.||:.
  Rat    74 -RGKRFSQNFREVAGRFLV--------------SETSSHLLVFGMEQRLPPNSELVQAMLRLFQE 123

  Fly   358 KQNRTDTASVNST---SAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQS--VNVQDE-WMKIDIEW 416
            ...||....:...   |||..:.:..:.|.:.      .:.:|..|.|  |::.:. |...|:..
  Rat   124 PVPRTALRRLERLPPHSAQARVTIEWLRVRED------GSNRTALIDSRLVSIYESGWKVFDVTE 182

  Fly   417 PIKHW-------------------------ISGHELSHLIQITCGGCDVSDME---EIISVD-KD 452
            .:..|                         .|.|:   |::....|......|   |:.::| ||
  Rat   183 AVNFWQQLSRPRQPLLLQVSVQREHLGPGTWSAHK---LVRFAAQGTPDGKGEPQLELHTLDLKD 244

  Fly   453 YRPFIVIDMQNRRRKSRQKRSINC------SSGMTECCREHLYISFRDIGWS-NWILKPEGYNAY 510
            |      ..|.           ||      :.| |.|||:.:|:..:.:.|: ||||:|.|:..|
  Rat   245 Y------GAQG-----------NCDPEAPVTEG-TRCCRKEMYLDLQGMKWAENWILEPPGFLIY 291

  Fly   511 FCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLE-----LVP-CCTAKQYSSLQLVVM---DS 566
            .|.|||..:.                      :||.     |.| .|.|.:.:||.::|.   |.
  Rat   292 ECVGSCRQLP----------------------ESLTIGWPFLGPRQCVASEMTSLPMIVSIKEDG 334

  Fly   567 SNTATVKTLPNMVVESCGC 585
            .....|.:||||.|::|.|
  Rat   335 KTRPQVVSLPNMRVQTCSC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	46/262 (18%)
		TGF_beta	481..585	CDD:278448	34/113 (30%)
Lefty2	NP_001007557.1	TGF-beta propeptide	45..231		32/214 (15%)
		TGFb_propeptide	<68..211	CDD:279078	25/163 (15%)
		TGF_beta	261..353	CDD:278448	34/113 (30%)
		transforming growth factor beta-like domain	263..353		33/111 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100