Protein Alignment daw and BMP10

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_055297.1
• Gene: BMP10 / 27302
• HGNCID: 20869
• Length: 424
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 104/479 - (21%)
• Similarity: 173/479 - (36%)
• Gaps: 133/479 - (27%)

  Fly   159 EESSLSSD-----DHFDDLSPLDFVRNELMAEDQQNQEKDLDLDLDLDQQPETPIEP-----EL- 212
            |:|.|..|     |.|.:...:||  |.|:...:....|.|:|. |:..|....::|     ||
Human    28 EQSPLEEDMSLFGDVFSEQDGVDF--NTLLQSMKDEFLKTLNLS-DIPTQDSAKVDPPEYMLELY 89

  Fly   213 --------PLGERNITISVKS--------SAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILE 261
                    .:...||..|.|:        |..|..|           ...|.::.|...::.|:.
Human    90 NKFATDRTSMPSANIIRSFKNEDLFSQPVSFNGLRK-----------YPLLFNVSIPHHEEVIMA 143

  Fly   262 KLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSKKFILLNREEVECNRARDGK 326
            :|||     .:.|:..:.|:||:                     .:|..:.  |.:|.....:|:
Human   144 ELRL-----YTLVQRDRMIYDGV---------------------DRKITIF--EVLESKGDNEGE 180

  Fly   327 SNPSMCFTFKI--DDADAEGFDVSTAV-LWL------------FKNKQNRTDTASVN----STSA 372
            .|..:..:.:|  .:::.|.|||:.|: .|.            .::|.:..:.||..    .|||
Human   181 RNMLVLVSGEIYGTNSEWETFDVTDAIRRWQKSGSSTHQLEVHIESKHDEAEDASSGRLEIDTSA 245

  Fly   373 QQ-----TIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWISGHELSHLIQ 432
            |.     .||.|:   ||..|.:.              ::|         :...||..:|..|..
Human   246 QNKHNPLLIVFSD---DQSSDKER--------------KEE---------LNEMISHEQLPELDN 284

  Fly   433 ITCGGCDVSDMEEIISVDKDYRPFIVIDMQNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGW 497
            :..........||.:   ...|..|:.|...|.|::.:.         ..|.|..|||.|::|||
Human   285 LGLDSFSSGPGEEAL---LQMRSNIIYDSTARIRRNAKG---------NYCKRTPLYIDFKEIGW 337

  Fly   498 SNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLV 562
            .:||:.|.||.||.|||.|:...:.....:.|:.|..::....:.|:.:  .||...:...:.::
Human   338 DSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASK--ACCVPTKLEPISIL 400

  Fly   563 VMDSSNTATVKTLPNMVVESCGCR 586
            .:|............|.|..||||
Human   401 YLDKGVVTYKFKYEGMAVSECGCR 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	43/237 (18%)
		TGF_beta	481..585	CDD:278448	29/103 (28%)
BMP10	NP_055297.1	TGFb_propeptide	55..256	CDD:279078	45/240 (19%)
		TGF_beta	321..423	CDD:278448	29/103 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810