Protein Alignment daw and GDF9

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_005251.1
• Gene: GDF9 / 2661
• HGNCID: 4224
• Length: 454
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 90/470 - (19%)
• Similarity: 162/470 - (34%)
• Gaps: 143/470 - (30%)

  Fly   215 GERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKP 279
            ||..|..|.:..:|..|.    ..::||.|.....|.....|  :|...| ..||::
Human    30 GEAQIAASAELESGAMPW----SLLQHIDERDRAGLLPALFK--VLSVGR-GGSPRL-------- 79

  Fly   280 IFDGMTLSHPDDSTKN--KELDDYYARTSKKFILLNREEV--------ECNRARDGKSN------ 328
                    .||....:  |:|...|| |.:.....||..:        .|.|.:....:
Human    80 --------QPDSRALHYMKKLYKTYA-TKEGIPKSNRSHLYNTVRLFTPCTRHKQAPGDQVTGIL 135

  Fly   329 PSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLS 393
            ||:...|.:|........:.:.:|:...|        ||:.:||.:  .|..:.:.:.|     |
Human   136 PSVELLFNLDRITTVEHLLKSVLLYNINN--------SVSFSSAVK--CVCNLMIKEPK-----S 185

  Fly   394 AAKTIAIQ----SVNVQDE------WMKIDIEWPIKHWISGHELS-HL-IQITCGGCDVSDMEEI 446
            :::|:...    :.|.|.|      |::||:...::..::.::.| |: |..||    :.|..|.
Human   186 SSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTC----MKDQLEH 246

  Fly   447 ISVDKD------YRPFIVI--------------DMQNRRRKSR---QKRSIN------------- 475
            .|....      ..|.:::              .:..:||.|:   |:||::
Human   247 PSAQNGLFNMTLVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLSAYPVGEEAAEDGR 311

  Fly   476 -----------------------CSSGMTECCREHLY-----------ISFRDIGWSNWILKPEG 506
                                   .|..::|..|:.|.           :||..:.|.|||:.|..
Human   312 SSHHRHRRGQETVSSELKKPLGPASFNLSEYFRQFLLPQNECELHDFRLSFSQLKWDNWIVAPHR 376

  Fly   507 YNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTAT 571
            ||..:|:|.|.........:..|:.:..|:... .:.|:.. |.|...:||.|.::.::...:..
Human   377 YNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK-LDSSVPR-PSCVPAKYSPLSVLTIEPDGSIA 439

  Fly   572 VKTLPNMVVESCGCR 586
            .|...:|:...|.||
Human   440 YKEYEDMIATKCTCR 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	47/247 (19%)
		TGF_beta	481..585	CDD:278448	26/114 (23%)
GDF9	NP_005251.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..330		0/26 (0%)
		TGF_beta	353..453	CDD:306518	23/101 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810