DRSC/TRiP Functional Genomics Resources

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Protein Alignment daw and GDF1

DIOPT Version :9

Sequence 1:NP_001259967.1 Gene:daw / 33474 FlyBaseID:FBgn0031461 Length:586 Species:Drosophila melanogaster
Sequence 2:NP_001374367.1 Gene:GDF1 / 2657 HGNCID:4214 Length:372 Species:Homo sapiens


Alignment Length:108 Identity:33/108 - (30%)
Similarity:64/108 - (59%) Gaps:6/108 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   483 CCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQA----ASHHSSIMKILSTSGANK 543
            |....||:|||::||..|::.|.|:.|.:|:|.|:...:::.:    |.:| ::::.|..:.|..
Human   267 CRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSGSGGPPALNH-AVLRALMHAAAPG 330

  Fly   544 SLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            :.:| |||...:.|.:.::..|:|:...::...:|||:.||||
Human   331 AADL-PCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGCR 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dawNP_001259967.1 TGFb_propeptide 244..458 CDD:279078
TGF_beta 481..585 CDD:278448 30/105 (29%)
GDF1NP_001374367.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 67..86
TGF_beta_GDF1_3_like 267..372 CDD:381642 31/106 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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