DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment daw and Bmp3

DIOPT Version :9

Sequence 1:	NP_001259967.1	Gene:	daw / 33474	FlyBaseID:	FBgn0031461	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_058801.1	Gene:	Bmp3 / 25667	RGDID:	2212	Length:	468	Species:	Rattus norvegicus

Alignment Length:	121	Identity:	42/121 - (34%)
Similarity:	67/121 - (55%)	Gaps:	5/121 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   466 RKSRQKRSINCSSGMTECCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHS 530
            :|:|:|:.|.    ...|.|.:|.:.|.|||||.||:.|:.::||:|.|:|......:...|:|:
  Rat   353 KKARRKQWIE----PRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHA 413

  Fly   531 SIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            :|..|:...|....:. .|||..::.|||.::..|.:....:|..|||.|:||.||
  Rat   414 TIQSIVRAVGVVSGIP-EPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVDSCACR 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078
daw	NP_001259967.1	TGF_beta	481..585	CDD:278448	36/103 (35%)
Bmp3	NP_058801.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..53
		TGFb_propeptide	46..>203	CDD:279078
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	72..93
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	316..349
		TGF_beta	364..467	CDD:278448	36/103 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910