Protein Alignment daw and Tgfb2

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001316036.1
• Gene: Tgfb2 / 21808
• MGIID: 98726
• Length: 442
• Species: Mus musculus
• Alignment Length: 441
• Identity: 102/441 - (23%)
• Similarity: 165/441 - (37%)
• Gaps: 129/441 - (29%)

  Fly   245 EQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPD-----DSTKN--------- 295
            :|....|||.::.|||.||:|...|:    :.|:|  |.:.   |:     :||::
Mouse    30 DQFMRKRIEAIRGQILSKLKLTSPPE----DYPEP--DEVP---PEVISIYNSTRDLLQEKASRR 85

  Fly   296 -------KELDDYYARTSKKFILLNREEVE----------------CNRARDGKSNPSMCF---- 333
                   :..::|||:...|..:.:....|                |:|     .:..:|.
Mouse    86 AAACERERSDEEYYAKEVYKIDMPSHLPSETVCPVVTTPSGSLGSFCSR-----QSQVLCGYLDA 145

  Fly   334 ---TFKIDDADAEGFDVSTAVLWLFKNKQN--RTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLS 393
               ||.........|||||    :.||..|  :.:.......:.:..:....:|:.|...||.|:
Mouse   146 IPPTFYRPYFRIVRFDVST----MEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLT 206

  Fly   394 AAKTIAIQS----VNVQDEWMKIDIEWPIKHWI--SGHELSHLIQITCGGCDV------------ 440
            :.....|.|    ...:.||:..|:...::.|:  ....|...|.:.|..|..
Mouse   207 SPTQRYIDSKVVKTRAEGEWLSFDVTDAVQEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKS 271

  Fly   441 ------------------SDMEEIISVDK---------------DYRPFIVIDMQNRRRKSRQKR 472
                              .|.:.|.|..|               .||   :...|:.|||.|...
Mouse   272 EELEARFAGIDGTSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYR---LESQQSSRRKKRALD 333

  Fly   473 SINCSSGMTE-CCREHLYISF-RDIGWSNWILKPEGYNAYFCRGSCSSV-ASVTQAASHHSSIMK 534
            :..|...:.: ||...|||.| ||:|| .||.:|:||||.||.|:|..: :|.||    |:.::.
Mouse   334 AAYCFRNVQDNCCLRPLYIDFKRDLGW-KWIHEPKGYNANFCAGACPYLWSSDTQ----HTKVLS 393

  Fly   535 ILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGC 585
            :.:|  .|......|||.::....|.::.. ..||..::.|.||:|:||.|
Mouse   394 LYNT--INPEASASPCCVSQDLEPLTILYY-IGNTPKIEQLSNMIVKSCKC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	56/309 (18%)
		TGF_beta	481..585	CDD:278448	39/106 (37%)
Tgfb2	NP_001316036.1	TGFb_propeptide	21..256	CDD:279078	49/243 (20%)
		TGF_beta	344..441	CDD:278448	39/104 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870