Protein Alignment daw and Nodal

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_038639.2
• Gene: Nodal / 18119
• MGIID: 97359
• Length: 354
• Species: Mus musculus
• Alignment Length: 472
• Identity: 96/472 - (20%)
• Similarity: 154/472 - (32%)
• Gaps: 164/472 - (34%)

  Fly   141 HRHVSPPVELPIMYGDAPEESS-----LSSDDHFDDLSPLDFVRNELMAED----QQN------- 189
            |........||:.....|...|     ||.  :.|.|...|.:|: |.|:|    .||
Mouse    19 HPRAPTAAALPLWTRGQPSSPSPLAYMLSL--YRDPLPRADIIRS-LQAQDVDVTGQNWTFTFDF 80

  Fly   190 ----QEKDL---DLDLDLDQQPETPIEPELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQL 247
                ||:||   :|.|.|....:.|.|..|       ||.:...|.|.|:.:....:|.|..|..
Mouse    81 SFLSQEEDLVWAELRLQLPGPMDIPTEGPL-------TIDIFHQAKGDPERDPADCLERIWMETF 138

  Fly   248 THL--RIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSKKFI 310
            |.:  ::.|....             :.:|:.||:              :|.|.|..|
Mouse   139 TVIPSQVTFASGS-------------TVLEVTKPL--------------SKWLKDPRA------- 169

  Fly   311 LLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQT 375
               .|:...:||......|   :|..:..|       ||.||.|:.|:
Mouse   170 ---LEKQVSSRAEKCWHQP---YTPPVPVA-------STNVLMLYSNR----------------- 204

  Fly   376 IVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWISGHELSHLIQITCGGCDV 440
                      .::.:.|..|..:          | :.:..|..:
Mouse   205 ----------PQEQRQLGGATLL----------W-EAESSWRAQ--------------------- 227

  Fly   441 SDMEEIISVDKDYRPFIVIDMQNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWSNWILKPE 505
               |..:||:             |....|::|..:.......|.|....:.|..|||.:||:.|:
Mouse   228 ---EGQLSVE-------------RGGWGRRQRRHHLPDRSQLCRRVKFQVDFNLIGWGSWIIYPK 276

  Fly   506 GYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVP--CCTAKQYSSLQLVVMDSSN 568
            .||||.|.|.|.:........::|:.|..:|.....::    ||  ||...:...|.::.:|:..
Mouse   277 QYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHR----VPSTCCAPVKTKPLSMLYVDNGR 337

  Fly   569 TATVKTLPNMVVESCGC 585
             ..::...:|:||.|||
Mouse   338 -VLLEHHKDMIVEECGC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	29/215 (13%)
		TGF_beta	481..585	CDD:278448	29/105 (28%)
Nodal	NP_038639.2	TGFb_propeptide	33..169	CDD:279078	39/172 (23%)
		TGFB	254..353	CDD:214556	29/103 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850418
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830