Protein Alignment daw and tig-2

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_504271.1
• Gene: tig-2 / 178864
• WormBaseID: WBGene00006570
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 394
• Identity: 80/394 - (20%)
• Similarity: 143/394 - (36%)
• Gaps: 115/394 - (29%)

  Fly   245 EQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSKKF 309
            :.||....:.:.:||.|...:..:|...||:....:...|...:       |:|::|....:.
 Worm    34 QPLTGQATDKIGEQIRELFNIDINPNGPAVKANNYVSTYMKRLY-------KQLENYEHGENH-- 89

  Fly   310 ILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQ- 373
               |.|||....:.|                        ..|..:.:...:|.|..|.:...|:
 Worm    90 ---NEEEVNAWLSAD------------------------RIVSHMAQEVSHRLDDGSYSIRFAKE 127

  Fly   374 -------QTIVVSEVEVDQQ----------KDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHW 421
                   |:||.:::.:..|          :|:..  ...|:.:.|   .|..:..|:...:..|
 Worm   128 HVPAKEGQSIVRAQLRIHIQGIVSPVFFYIEDTNL--PGDTVLVSS---DDPTVVTDVTTMVDRW 187

  Fly   422 ISGHELSHL----IQITCGGCDVSDMEEIISVDKDYRPFIVIDMQNRRR---KSRQKRSINCS-- 477
                  |||    :.|.......:|..:|       ..|:||.:::...   |.|.:||.:.:
 Worm   188 ------SHLQLSTLPIVTARASTNDELKI-------EAFLVIALKDEDAGPPKKRSRRSASTTPI 239

  Fly   478 -------------SGMTE-------CCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASV 522
                         |...|       |.|:.||:.|..:||..|::.|||::|::|.|.||:..|.
 Worm   240 SAPPMRQKVKRSESAYFEKPNENERCQRKGLYVDFDILGWKQWVIAPEGFSAFYCSGDCSAPFSK 304

  Fly   523 TQAASHHSSIMKIL------STSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVE 581
            ...|:.|:.:...|      ||:.|.        |......|.:::.:|.:....:|...:|||:
 Worm   305 EMNATSHAIVQSTLHRVRPNSTTPAK--------CAPSSLGSYKILFVDQNKQVQIKRYRDMVVD 361

  Fly   582 SCGC 585
            .|||
 Worm   362 ECGC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	39/234 (17%)
		TGF_beta	481..585	CDD:278448	32/116 (28%)
tig-2	NP_504271.1	TGF_beta_BMP5_like	264..366	CDD:381639	33/110 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810