Protein Alignment daw and emb-30

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_499074.2
• Gene: emb-30 / 176322
• WormBaseID: WBGene00001284
• Length: 1027
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 102/539 - (18%)
• Similarity: 180/539 - (33%)
• Gaps: 215/539 - (39%)

  Fly    62 HIRQQRSRQLKHLEPDPTSEEDDVPITKREYYARLRRHVIHKRQHLLQQ-ELSYNHPGSHSEQLK 125
            ::::..|:|.|   .|...:.|:|     ||..||.|....:|:.|::. ...:.......:.|
 Worm   541 NLKELVSKQKK---KDLEDKFDEV-----EYLYRLERIAEVERKKLIETFHEKFRFADLDDDDL- 596

  Fly   126 VPRLWQHLMEQEEKAHRHVSPPVELPIMYGDAPEESSLSSDDHFDDLSPLDFVRNELMAEDQQNQ 190
            .|.|:|.|           ..|:::   :.|:..|.        :|.||       .:.||:...
 Worm   597 TPLLFQEL-----------DHPIDI---FTDSMMEQ--------NDSSP-------FLEEDEGEP 632

  Fly   191 EKDLDLDLDLDQQPETPIEPELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFV 255
            |::       :|:|:...|||   ||..            |.|:.:| |....|::|:...:|.:
 Worm   633 EQE-------EQKPDEEPEPE---GEPQ------------PACDLDR-VGSFFEKELSQKALEVL 674

  Fly   256 KQ--QILEKLRLKESPKVSAVELPK----PIFDGM--TLSHP-----DDSTKNKELD-------- 299
            .:  :..:.:..:...:::::|:.|    .:.:.:  |||.|     |.:...|:|:
 Worm   675 PKCDETFDCVLNERGSRMNSIEIQKMGILRVLEDLAATLSSPQKIHCDKAGNQKKLEVSFIYEIT 739

  Fly   300 ------------------DYYAR----------TSKKFILLNREEVEC--------------NRA 322
                              .||.|          .|.:..:|.:.|...              |..
 Worm   740 STPTHQGYQDAKISSVTPSYYKRHPFNQLSGMGRSIQVSVLQKNEFSSIVIVPTSDVLPEDENEV 804

  Fly   323 RDGKSNPSMCFTF-KIDDADAEGFDVSTAVLWLFKNKQNR----TDTASVNS------------- 369
            .|.......|:.| |||..    .|.|:|        :||    ||...|:|
 Worm   805 NDHVEKLKRCYEFEKIDVT----VDKSSA--------ENRPPGETDAMEVDSNELRIDVDLGPVV 857

  Fly   370 --------------------------TSAQQ-TIVVSEV---------EVDQQKDSKYLSAAKTI 398
                                      ||||: |.|:|::         |:.:.||
 Worm   858 PEYDTLIELSQVHPLHHGELVLLGKFTSAQEGTGVMSQMMRSISSYPHEIPEDKD---------- 912

  Fly   399 AIQSVNVQDEWMKIDIEWPIKH---WISGHELSHLIQITCGGC-----DVSDMEEIISVDKDYRP 455
            .....:.:|...:|.||..|.|   .::.:......:||.|..     .::|.|| .:|.|.:|
 Worm   913 VFAKNSSEDGSSEIPIETLIIHPTIQLAAYLHDDGSKITIGDMKPEVPPIADYEE-KTVRKTFR- 975

  Fly   456 FIVIDMQNRRRKSRQKRSI 474
                |.|.||.:.|:...:
 Worm   976 ----DYQRRRERYREDMGV 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	59/338 (17%)
		TGF_beta	481..585	CDD:278448
emb-30	NP_499074.2	ANAPC4_WD40	2..56	CDD:289649
		WD40	<21..118	CDD:225201
		WD40	<23..122	CDD:295369
		WD40 repeat	24..70	CDD:293791
		WD40 repeat	75..111	CDD:293791
		WD40 repeat	118..154	CDD:293791

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.807993	Normalized mean entropy	S5
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950