DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment daw and Mcm3

DIOPT Version :9

Sequence 1:	NP_001259967.1	Gene:	daw / 33474	FlyBaseID:	FBgn0031461	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_032589.1	Gene:	Mcm3 / 17215	MGIID:	101845	Length:	812	Species:	Mus musculus

Alignment Length:	159	Identity:	34/159 - (21%)
Similarity:	59/159 - (37%)	Gaps:	35/159 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   252 IEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSKKFILLNREE 316
            :|.|:....:|:..||..:..|.|      |...|.  |:..|::| |....|..:|
Mouse   646 VELVQYAYFKKVLEKEKKRKKASE------DESDLE--DEEEKSQE-DTEQKRKRRK-------- 693

  Fly   317 VECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEV 381
               ..|:||:|              .:.:|.|.|...:.:....:||.:...:..:|:|....:|
Mouse   694 ---THAKDGES--------------YDPYDFSEAETQMPQVHTPKTDDSQEKTDDSQETQDSQKV 741

  Fly   382 EVDQQKDSKYLSAAKTIAIQSVNVQDEWM 410
            |:.:.: .|...||.....|..:.|...|
Mouse   742 ELSEPR-LKAFKAALLEVFQEAHEQSVGM 769

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	34/159 (21%)
daw	NP_001259967.1	TGF_beta	481..585	CDD:278448
Mcm3	NP_032589.1	MCM_N	17..129	CDD:291233
		MCM	109..654	CDD:214631	2/7 (29%)
		P-loop_NTPase	340..479	CDD:304359
		Arginine finger	477..480
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	664..744		23/113 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.807993	Normalized mean entropy	S5
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950