Protein Alignment daw and Inhba

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_032406.1
• Gene: Inhba / 16323
• MGIID: 96570
• Length: 424
• Species: Mus musculus
• Alignment Length: 413
• Identity: 102/413 - (24%)
• Similarity: 168/413 - (40%)
• Gaps: 73/413 - (17%)

  Fly   226 SAGGCPKCE--------SNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPK-PIF 281
            ||..||.|.        .|.|.|          .:|.||:.||..|.||:.|.|:. .:|| .:.
Mouse    31 SAPDCPSCALATLPKDGPNSQPE----------MVEAVKKHILNMLHLKKRPDVTQ-PVPKAALL 84

  Fly   282 DGMTLSHPDDSTKN--KELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEG 344
            :.:...|.....:|  .|::|...|.::...|:.:.......|..|.:..::.|     :...||
Mouse    85 NAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHF-----EISKEG 144

  Fly   345 FDVST---AVLWLFKN--KQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVN 404
            .|:|.   |.:|||..  |.|||.|........||......::...:.:...|...::..:.|..
Mouse   145 SDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGDEAEEMGLKGERSELLLSEK 209

  Fly   405 VQD----EWMKIDIEWPIKHWISGHELSHLIQITCGGCDVSDMEEII-------SVDKD------ 452
            |.|    .|....:...|:..:...:.|..::|.|..|..|....::       .||.|
Mouse   210 VVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDGDGKKKDG 274

  Fly   453 ------------YRPFIVI------DMQNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWSN 499
                        :|||:::      |..:|||    :|.:.|...:..||::..::||:||||::
Mouse   275 SDGGLEEEKEQSHRPFLMLQARQSEDHPHRRR----RRGLECDGKVNICCKKQFFVSFKDIGWND 335

  Fly   500 WILKPEGYNAYFCRGSCSSVASVTQAA--SHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLV 562
            ||:.|.||:|.:|.|.|.|..:.|..:  |.||:::......|.:....|..||...:...:.::
Mouse   336 WIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSML 400

  Fly   563 VMDSSNTATVKTLPNMVVESCGC 585
            ..|.......|.:.||:||.|||
Mouse   401 YYDDGQNIIKKDIQNMIVEECGC 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	33/103 (32%)
Inhba	NP_032406.1	TGFb_propeptide	56..291	CDD:480997	52/240 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..306		8/41 (20%)
		TGF_beta_INHBA	317..424	CDD:381674	35/107 (33%)