Protein Alignment daw and Gdf5

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_032135.2
• Gene: Gdf5 / 14563
• MGIID: 95688
• Length: 495
• Species: Mus musculus
• Alignment Length: 476
• Identity: 98/476 - (20%)
• Similarity: 181/476 - (38%)
• Gaps: 111/476 - (23%)

  Fly   135 EQEEKAHRHVSPPVELPIMYGDAPEESSLSSDDHFDDLSPLDFVRNELMAEDQQNQEKDLDLDLD 199
            :..:.|.|.|:|..:||  .|.|..::.         .:|..|:                   |.
Mouse   107 QTRQAAARTVTPKGQLP--GGKASSKAG---------SAPSSFL-------------------LK 141

  Fly   200 LDQQPETPIEPELPLGERNIT-----ISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQI 259
            ..::|.||.||:.|.....||     :|:..:.....:...|..|:  .|..|.:....|:.:
Mouse   142 KTREPGTPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGNSSVK--LEAGLANTITSFIDK-- 202

  Fly   260 LEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSKKFILLNRE--------- 315
                  .:..:..||...:.:||...|.  .|.....||.           :|.::
Mouse   203 ------GQDDRGPAVRKQRYVFDISALE--KDGLLGAELR-----------ILRKKPLDVAKPAV 248

  Fly   316 -------EVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLW-LFKNKQNRTDTASVNSTSA 372
                   :::.:....|:...::.....:...|..|::|..  :| ||:|.:|          ||
Mouse   249 PSSGRVAQLKLSSCPSGRQPAALLDVRSVPGLDGSGWEVFD--IWKLFRNFKN----------SA 301

  Fly   373 QQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWISGHELSHLIQITCGG 437
            |..:.:...|..:..|.:.|...:|    :..|.::.:.:......|..:..:|    |:...|.
Mouse   302 QLCLELEAWERGRAVDLRGLGFERT----ARQVHEKALFLVFGRTKKRDLFFNE----IKARSGQ 358

  Fly   438 CDVSDMEEIISVDKDYRPFIVIDMQNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWSNWIL 502
            .|.:..|.:.|..:..|    ..:.||:.| |..:::.     ..|.|:.|:::|:|:||.:||:
Mouse   359 DDKTVYEYLFSQRRKRR----APLANRQGK-RPSKNLK-----ARCSRKALHVNFKDMGWDDWII 413

  Fly   503 KPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVP--CCTAKQYSSLQLVVMD 565
            .|..|.|:.|.|.|..........::|:.|..::::...    |..|  ||...:.|.:.::.:|
Mouse   414 APLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDP----ESTPPTCCVPTRLSPISILFID 474

  Fly   566 SSNTATVKTLPNMVVESCGCR 586
            |:|....|...:|||||||||
Mouse   475 SANNVVYKQYEDMVVESCGCR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	37/230 (16%)
		TGF_beta	481..585	CDD:278448	32/105 (30%)
Gdf5	NP_032135.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..162		17/84 (20%)
		TGFb_propeptide	139..338	CDD:279078	41/256 (16%)
		TGFB	394..495	CDD:214556	33/104 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810