Protein Alignment daw and Bmp8b

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_031585.2
• Gene: Bmp8b / 12164
• MGIID: 107335
• Length: 399
• Species: Mus musculus
• Alignment Length: 390
• Identity: 95/390 - (24%)
• Similarity: 162/390 - (41%)
• Gaps: 93/390 - (23%)

  Fly   255 VKQQILEKLRLKESPK----VSAVELP--KPIF-----DGMTLSHPDDS---TKNKELDDYYART 305
            ::::|.|.|.|...|:    |.|.:.|  .|:|     ..||    |||   |....||  .|..
Mouse    43 MQREIREVLGLPGRPRSRAPVGAAQQPASAPLFMLDLYRAMT----DDSGGGTPQPHLD--RADL 101

  Fly   306 SKKFILLNREEVECNRARDGKSNPSMC-FTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNS 369
            ...|:.:    ||.:|.. |...|... |.|.:....| |..|:.|...::|    ...|..:|:
Mouse   102 IMSFVNI----VERDRTL-GYQEPHWKEFHFDLTQIPA-GEAVTAAEFRIYK----EPSTHPLNT 156

  Fly   370 TSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDE-WMKIDIEWPIKHWISGH--ELSHLI 431
                 |:.:|..||.|:..::. |....:.:|::...|| |:.:||......|:..|  :|...:
Mouse   157 -----TLHISMFEVVQEHSNRE-SDLFFLDLQTLRSGDEGWLVLDITAASDRWLLNHHKDLGLRL 215

  Fly   432 QITCGGCDVSDMEEIISVD------------KDYRPFIV-----------IDMQNRRRKSRQKRS 473
            .:        :.|:..|:|            :..:||:|           .....|..|.:|...
Mouse   216 YV--------ETEDGHSIDPGLAGLLGRQAPRSRQPFMVGFFRANQSPVRAPRTARPLKKKQLNQ 272

  Fly   474 IN----------------CSSGMTECCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASV 522
            ||                .|.|...|.|..||:||||:||.:.::.|:||:||:|.|.|....:.
Mouse   273 INQLPHSNKHLGILDDGHGSHGREVCRRHELYVSFRDLGWLDSVIAPQGYSAYYCAGECIYPLNS 337

  Fly   523 TQAASHHSSIMKILSTSGANKSLELVP--CCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGC 585
            ...:::|:::..::..    ...:::|  ||...:.|::.|:..|.:|...::...||||::|||
Mouse   338 CMNSTNHATMQALVHL----MKPDIIPKVCCVPTELSAISLLYYDRNNNVILRRERNMVVQACGC 398

  Fly   586  585
            Mouse   399  398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	31/103 (30%)
Bmp8b	NP_031585.2	TGFb_propeptide	32..248	CDD:459906	55/234 (24%)
		TGF_beta_SF	295..399	CDD:477357	33/108 (31%)