Protein Alignment daw and Bmp4

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_031580.2
• Gene: Bmp4 / 12159
• MGIID: 88180
• Length: 408
• Species: Mus musculus
• Alignment Length: 455
• Identity: 95/455 - (20%)
• Similarity: 159/455 - (34%)
• Gaps: 146/455 - (32%)

  Fly   204 PETPIEPELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKES 268
            |||        |::.:. .::..|||   ..|.:..|.:.:.:.|.|:        :..||.:..
Mouse    28 PET--------GKKKVA-EIQGHAGG---RRSGQSHELLRDFEATLLQ--------MFGLRRRPQ 72

  Fly   269 PKVSAVELPKPIFD----------------GMTLSHPDDSTKNKELDDYYARTSKKFILLNREEV 317
            |..||| :|..:.|                |..|.:|:.....       |.|.:.|  .:.|.:
Mouse    73 PSKSAV-IPDYMRDLYRLQSGEEEEEEQSQGTGLEYPERPASR-------ANTVRSF--HHEEHL 127

  Fly   318 ECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVE 382
            |                      :..|...|:|..:||            |.:|..:..|:|..|
Mouse   128 E----------------------NIPGTSESSAFRFLF------------NLSSIPENEVISSAE 158

  Fly   383 -------VDQQKDSKYLSAAKTIAIQSVNVQD----------------------------EWMKI 412
                   |||..|.:.       ....:|:.:                            .|...
Mouse   159 LRLFREQVDQGPDWEQ-------GFHRINIYEVMKPPAEMVPGHLITRLLDTRLVHHNVTRWETF 216

  Fly   413 DIEWPIKHWIS--------GHELSHLIQI-TCGGCDVSDMEEIISVDKDY---RPFIVI------ 459
            |:...:..|..        ..|::||.|. |..|..|.....:.....|:   ||.:|.
Mouse   217 DVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGDWAQLRPLLVTFGHDGR 281

  Fly   460 --DMQNRRRKSRQKRSINCSSGMTECCREH-LYISFRDIGWSNWILKPEGYNAYFCRGSCSSVAS 521
              .:..||.|...|.....|....:.||.| ||:.|.|:||::||:.|.||.|::|.|.|....:
Mouse   282 GHTLTRRRAKRSPKHHPQRSRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLA 346

  Fly   522 VTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            ....:::|:.:..::::  .|.|:... ||...:.|::.::.:|..:...:|....||||.||||
Mouse   347 DHLNSTNHAIVQTLVNS--VNSSIPKA-CCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 408

  Fly   587  586
            Mouse   409  408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	31/102 (30%)
Bmp4	NP_031580.2	TGFb_propeptide	43..276	CDD:459906	51/294 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..111		3/19 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..307		5/25 (20%)
		TGF_beta_BMP4_BMP2B	302..408	CDD:381661	32/108 (30%)