Protein Alignment daw and gdf11

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_002934559.1
• Gene: gdf11 / 100492886
• XenbaseID: XB-GENE-487193
• Length: 384
• Species: Xenopus tropicalis
• Alignment Length: 410
• Identity: 108/410 - (26%)
• Similarity: 173/410 - (42%)
• Gaps: 81/410 - (19%)

  Fly   203 QPETPIEPELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKE 267
            |.:..::.||.|||        |....||.|...:   |..|     :|:|.:|.|||.||||||
 Frog    28 QQKGSLQVELTLGE--------SEEQDCPVCTWRK---HSKE-----MRLESIKSQILSKLRLKE 76

  Fly   268 SPKVSA----VELPK--PI--------FDGMTLSHPDDSTKNKELDDYYARTSKKFILLNREEVE 318
            :|.:|.    ..|||  |:        |.|.:..|   :|..:| |:|:| |::..|.:.:|...
 Frog    77 APNISREIVNQLLPKAPPLQQILDQHEFQGDSFQH---NTFLEE-DEYHA-TTETVISMAQETDH 136

  Fly   319 CNRARDGKSNPSMC---FTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSE 380
            ..|. ||  ||..|   |:.||...     .|..|.||::......|.|..:      |.:.:..
 Frog   137 AVRI-DG--NPHCCYFNFSPKIMFT-----KVVKAQLWVYLRPVQHTSTVYL------QILRLKP 187

  Fly   381 VEVDQQKDSKYLSAAKTIAIQSVNV-----QDEWMKIDIEWPIKHWISGHELSHLIQITCGGCDV 440
            |..:         .:|.|.|:|:.:     ...|..||.:..:::|......:..|:|.....:.
 Frog   188 VTEE---------GSKHIRIRSLKIDLHSRSGHWQSIDFKHVLQNWFKQPHNNWGIEINAFDPNG 243

  Fly   441 SDMEEIISVD---KDYRPFIVIDMQNRRRKSRQKRSINCSSGMTE--CCREHLYISFRDIGWSNW 500
            :|: .:.|:.   :...||:.:.:....::||:...::|....||  |||..|.:.|...|| :|
 Frog   244 NDL-AVTSLGPGAEGLHPFMELRVMENNKRSRRNLGLDCDEHSTESRCCRYPLTVDFEAFGW-DW 306

  Fly   501 ILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMD 565
            |:.|:.|.|.:|.|.|..:  ..|...|...:.:      ||......||||..:.|.:.::..:
 Frog   307 IIAPKRYKANYCSGQCEYM--FMQKYPHTHLVQQ------ANPRGSAGPCCTPTKMSPINMLYFN 363

  Fly   566 SSNTATVKTLPNMVVESCGC 585
            .........:|.|||:.|||
 Frog   364 DKQQIIYGKIPGMVVDRCGC 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	29/101 (29%)
gdf11	XP_002934559.1	TGFb_propeptide	47..262	CDD:480997	64/251 (25%)
		TGF_beta_GDF8	278..384	CDD:381658	34/115 (30%)