Protein Alignment daw and nodal2

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_002932767.1
• Gene: nodal2 / 100491883
• XenbaseID: XB-GENE-487474
• Length: 405
• Species: Xenopus tropicalis
• Alignment Length: 406
• Identity: 83/406 - (20%)
• Similarity: 161/406 - (39%)
• Gaps: 61/406 - (15%)

  Fly   211 ELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVE 275
            ::||...|:.....|::.|....:..|....:.:...|.:........|||...|:||..|.::
 Frog    29 KIPLAGSNLGYKKSSNSYGSRLSQGMRYPPSMMQLYQTLILGNDTDLSILEYPILQESDAVLSL- 92

  Fly   276 LPKP---IFDGMTLSHPDDS-TKNKELDDYYARTSKKFILLNREE---VECNRARDGKSNPSMCF 333
            :.|.   :.:..|||....| :.:.||.  .|....:.....|.:   ||....:||:.|..| .
 Frog    93 IAKSCDVVGNRWTLSFDMSSISSSNELK--LAELRIRLPSFERSQDVTVEIYHTKDGQENLFM-G 154

  Fly   334 TFKIDDADAEG-----FDVSTAVLWLFKNKQNRTDTASVNSTSAQQTI----------VVSEVEV 383
            :||.:.:.|.|     |:::..:.:...:.:..|:...:...:..:.:          ..:|..:
 Frog   155 SFKTNPSVAMGSSWKVFNLTKMLQYYLHHGEPFTNDEYIEVKNLHERVRPRVIKRGARTEAEEGL 219

  Fly   384 DQQKDSKYLSAAKT-IAIQSVNVQDEWMKIDIEWPIKHWISGHELSHLIQITCGGCDVSDMEEII 447
            .:.||:..:|:..| ..:..|..:|:        |..::.....|.|.:          :..:.:
 Frog   220 QRNKDNTPVSSFPTDKVVLVVFTRDK--------PTANYFGSPSLIHTV----------ESSKYV 266

  Fly   448 SVDKDYRPFIVIDMQNRRRKSRQKRSINCSS------GMTECCREHLYISFRDIGWSNWILKPEG 506
            ..:...|   |.|.:..||..:.|.||..::      |.|.|.|..:.:.|..|.|.:.|:.|:.
 Frog   267 MSESTVR---VADTRRHRRNQKTKNSIVMNTMPSRYVGKTLCRRVDMIVDFEKIEWGDRIVYPKR 328

  Fly   507 YNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPC--CTAKQYSSLQLVVMDSSNT 569
            :|||.|.|:|....:.|...::|:.|..::......|    |.|  |...:.|.|.:::.:...
 Frog   329 FNAYRCEGACPIPLNETFKPTNHAYIKSLVKLYDEEK----VECSSCIPVKMSPLSMLLYEDGE- 388

  Fly   570 ATVKTLPNMVVESCGC 585
            ..:|...:|:|:.|||
 Frog   389 VVLKHHEDMIVDECGC 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	26/103 (25%)
nodal2	XP_002932767.1	TGF_beta_NODAL	303..404	CDD:381637	27/105 (26%)