Protein Alignment daw and bmp16

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001165247.1
• Gene: bmp16 / 100329171
• ZFINID: ZDB-GENE-100115-1
• Length: 416
• Species: Danio rerio
• Alignment Length: 616
• Identity: 117/616 - (18%)
• Similarity: 202/616 - (32%)
• Gaps: 243/616 - (39%)

  Fly     8 LVLLVCLALENRNVYNRLHARSHPSSRGDILRPHPKHQPHPHVQHTSQQL------QQQHHIRQQ 66
            |||::.|..:..:.:....:::|  .:.|.|.       .|.:.||.|.|      .|.|
Zfish     7 LVLMILLLPQASSGHQEGPSQTH--GKLDSLL-------EPSLAHTIQNLLLTRLGLQSH----- 57

  Fly    67 RSRQLKHLEPDPTSEEDDVPITKREYYARLRRHVIHKRQHLLQQELSYNHPGSHSEQLKVPRLWQ 131
                     |:| |.:..||    :|...|.|  .|.:|:.|.::..:::|..|.:.....|.:.
Zfish    58 ---------PNP-STKAQVP----QYLLDLYR--FHTQQYHLIEDPEFSYPSKHVQGANTVRCFH 106

  Fly   132 HLMEQEEKAHRHVSPPVELPIMYGDAPEESSLSSDDHFDDLSPLDFVRNELMAEDQQNQEKDLDL 196
            |.                      |:|..|                     :.|:|:.....:.:
Zfish   107 HT----------------------DSPTPS---------------------LPEEQKTTVDGIHI 128

  Fly   197 DLDLDQQP--ETPIEPELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQI 259
            ..:|...|  |:.:..||.|..       :.|:||          .|:.
Zfish   129 GFNLSSIPSEESVVSAELRLLH-------EGSSGG----------SHVA---------------- 160

  Fly   260 LEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSKKFILLNREEVECNRARD 324
                                   .:.||:.|.|:|.              |||:..::    .||
Zfish   161 -----------------------SLYLSNHDPSSKP--------------ILLHSRQL----TRD 184

  Fly   325 GKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDS 389
            .|| ..:..||.:|..             :|:|         ::.||...:.::.  .:.....|
Zfish   185 RKS-AQLWETFPLDRE-------------VFQN---------LSKTSGSLSFILD--VIPDSNSS 224

  Fly   390 KYLSAAKTIAIQSVNVQD--EWMKIDIEWPIKHWISGHELSHLIQITCGGCDVSDMEEIISVDKD 452
            ..|...:.:.::...:||  .|.:   :.|:                           :::...|
Zfish   225 STLPKDRHLRVRRSTLQDGPTWER---QRPL---------------------------LVTYSHD 259

  Fly   453 YR--PFIVI-----------------------DMQNRRRKSRQKRSINCSSGMTECCREH-LYIS 491
            .|  ||:.:                       |...||.|...:|:..........||.| ||:.
Zfish   260 GRSEPFVNLNKRKSSRSRSRWTRFKGDRGQGSDWNERRVKRNNRRAAKLKRLSRARCRRHPLYVD 324

  Fly   492 FRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILST-SGANKSLELVPCCTAKQ 555
            |:|:||:.||:.|.||:|:||.|.|....:....:|.|:.:..::|: :||...    |||....
Zfish   325 FKDVGWNKWIIAPSGYDAFFCLGECRFPLADHMNSSSHAMVQTLVSSVNGAVPR----PCCVPTA 385

  Fly   556 YSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            .|.:.|:.:|......:|...:||||.||||
Zfish   386 LSPIALLFLDQEERVVLKNYQDMVVEGCGCR 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	36/103 (35%)
bmp16	NP_001165247.1	TGFb_propeptide	44..256	CDD:480997	59/404 (15%)
		TGF_beta_SF	314..416	CDD:477357	37/105 (35%)