Protein Alignment Syt1 and TCB2

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_014312.1
• Gene: TCB2 / 855637
• SGDID: S000005031
• Length: 1178
• Species: Saccharomyces cerevisiae
• Alignment Length: 338
• Identity: 82/338 - (24%)
• Similarity: 142/338 - (42%)
• Gaps: 71/338 - (21%)

  Fly   142 RTKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQK-------------- 192
            ||.:..||||| ..:|....|.|.......:||..|..|..:::||..:||
Yeast   757 RTGNLIGKKGV-KGTVTYYLSFYPVVPVLSLEEAKEVDEINEKKDKLEKQKSTLDDKNISKEEKE 820

  Fly   193 -LGRLNFKL--EYD---------------FNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPD 239
             :.:..|:|  :||               :|:..|.|||: ..|||...:      ||:.:
Yeast   821 RIKKEEFRLTEKYDMYSYKMKLDLDELLQYNAGVLGVTVL-GGELPQPGL------YVQTF---- 874

  Fly   240 KKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDF------DRFSKHDQIGEVKVP 298
                |::..: ..::...|...|.|:....|.|.|.|.:::..|      |.....:.|.||.:|
Yeast   875 ----FDSCGY-AAITSAKNAIRTIKTGWSGDFMIKELEWSVTTFRVTKTKDANKAENFICEVNIP 934

  Fly   299 LCTIDLAQTIEEWRDLVSVEGEGGQEKLGDICF---------SLRYVPTAGKLTVVILEAKNLKK 354
              ||:|.:.......::::.|:...:.|..:.:         ....:..:|.|.:....|:||..
Yeast   935 --TIELVRNCYYKPSVLNLIGKKSAKLLVQVSWFPVTATELPQSDLITNSGDLKITAKSAENLIG 997

  Fly   355 MDVGGLSDPYVKIAIMQNGKRLKK-KKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYD 418
            ::..|.|||||:..:  |.|.... .||:::|.||||.:|||.:.||. .::... |.:.|.||:
Yeast   998 VNKNGYSDPYVEFFL--NEKSTSPFFKTAVQKKTLNPTWNESKTIEVS-NRVNDY-LTINVKDYE 1058

  Fly   419 RIGTSEPIGRCIL 431
            ...::..||:.::
Yeast  1059 STNSNRSIGKAVV 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	8/18 (44%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	32/161 (20%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	32/116 (28%)
TCB2	NP_014312.1	COG5038	4..1178	CDD:227371	82/338 (24%)