Protein Alignment Syt1 and TCB3

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_013639.1
• Gene: TCB3 / 854903
• SGDID: S000004537
• Length: 1545
• Species: Saccharomyces cerevisiae
• Alignment Length: 390
• Identity: 76/390 - (19%)
• Similarity: 161/390 - (41%)
• Gaps: 99/390 - (25%)

  Fly    22 EPAADLESVDQKLEETHHSKFREVDRQEQEVLAEKAAEAASQRIAQVE----STTRSATTEA--- 79
            |...::|.::::|:| ...|| |..::|.|...||  ......:|::|    |..:....:|
Yeast   939 EELVNVEKLEKELKE-KKKKF-EATQEENEQEMEK--NPKEWEVAEIEDPFDSDEKKINRKAKLS 999

  Fly    80 ------QESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCVRRFL 138
                  |:|...::.:::..........|::|:....|                  :|.|:
Yeast  1000 LNELIKQKSGILSMQILEGTLSPSSAYLEILADDISYP------------------VFICM---- 1042

  Fly   139 KKRRTKDGKGKKGVDMKSVQLLGSAY--------KEKVQPDMEE-LTENAEEGDEEDKQSEQKLG 194
                 |..:||...:|.::.:....|        |:.:..|.:: ::|.:....:..||:.::..
Yeast  1043 -----KPSQGKLNSEMANIFIRDLNYSKLHFRVSKKHIAKDSDDVISETSYSTLKLLKQAYEEPM 1102

  Fly   195 RLNF---KLEYDF----------------NSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDK 240
            .|||   |::..|                ::..|.:.:|....|.:.|..|.|||:|.:::  :.
Yeast  1103 WLNFNGSKMKVRFLYTPTSVKLPSSESVEDTGYLNIKLISGHGLKSADRNGYSDPFVHIFV--ND 1165

  Fly   241 KKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLA 305
            ||.|::.:.:|||.||:||.   ..:|........::|.:.|:||...:|.:|:..:.:.::::.
Yeast  1166 KKVFKSNIKKKTLDPVWNED---AKIPILSRSKNQVIFNVLDWDRAGDNDDLGQASLDVSSLEVG 1227

  Fly   306 QTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDV--GGLSDPYVKIA 368
            :|. .|.  :::..:|..:..|.  |:..|:..:               .|:  ||::|..:|||
Yeast  1228 KTY-NWN--LNLNTQGSIKLQGS--FNPEYIKPS---------------FDIVKGGITDKPMKIA 1272

  Fly   369  368
            Yeast  1273  1272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	22/126 (17%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	33/142 (23%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	10/45 (22%)
TCB3	NP_013639.1	COG5038	44..1335	CDD:227371	76/390 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	1	1.000	-	-		otm46764
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910