Protein Alignment Syt1 and Syt13

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_109650.1
• Gene: Syt13 / 80976
• MGIID: 1933945
• Length: 426
• Species: Mus musculus
• Alignment Length: 464
• Identity: 114/464 - (24%)
• Similarity: 185/464 - (39%)
• Gaps: 95/464 - (20%)

  Fly    10 DAKPEAEPA-PASEPAADLESVDQKLEETHHS---KFREVDRQEQEVLAEKAAEAASQRIAQVES 70
            |.:|:.|.| |....||...::.:..|.....   ||.::......|.|.:....|...:...|.
Mouse    43 DREPDPEKARPGVLQAAQQFNIKKSTEPVQPRPLLKFPDIYGPRPAVTAPEVINYADYTLETTEE 107

  Fly    71 TTRSATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCVR 135
            :...|:.:||..:           .:...|||.::.|   |..|||..:             ||
Mouse   108 SAAPASPQAQSDS-----------RLKRQVTEELSIR---PQNGVVEDV-------------CV- 144

  Fly   136 RFLKKRRTKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKL 200
                                                       .|..:.|...|..:..:|:|:|
Mouse   145 -------------------------------------------METWNPEKAASWNQAPKLHFRL 166

  Fly   201 EYDFNSNSLAVTVIQAEELPALDMGGTSDPYVK-VYLLPDKKKKFETKVHRKTLSPVFNETFTF- 263
            :||.....|.||.::|   ...|..|..|.|:: ...:.....:.:|.:.::.|...:.|....
Mouse   167 DYDQKKAELFVTSLEA---VTSDHEGGCDCYIQGSVAVKTGSVEAQTALKKRQLHTTWEEGLALP 228

  Fly   264 ---KSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDL--VSVEGEGGQ 323
               :.||.|     ||...:...||||:|..|||:::.|....:.....:|.:|  .:.|...|
Mouse   229 LGEEELPTA-----TLTLTLRTCDRFSRHSVIGELRLGLDGASVPLGAAQWGELKTTAKEPSAG- 287

  Fly   324 EKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGL--SDPYVKIAIMQNGKRLKKKKTSIKKC 386
              .|::..|:.|:|.|.:|.||:::||||.......|  .|..||:.:....::||||:|...|.
Mouse   288 --AGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQAQKLKKKQTKRAKH 350

  Fly   387 TLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPR 451
            .:||.:||...||:|.:.::...:.:.|:.....|.|..:|.|.||...:|:|..||.:||.:||
Mouse   351 KINPVWNEMIMFELPDDLLRASSVELEVLGQGEEGPSCELGHCSLGLHASGSERSHWEEMLKNPR 415

  Fly   452 RPIAQWHTL 460
            |.||.||.|
Mouse   416 RQIAMWHQL 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	27/129 (21%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	32/130 (25%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	50/137 (36%)
Syt13	NP_109650.1	C2	160..277	CDD:301316	31/124 (25%)
		C2B_Synaptotagmin-13	288..425	CDD:176052	50/137 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820