Protein Alignment Syt1 and syt7

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_031756132.1
• Gene: syt7 / 780295
• XenbaseID: XB-GENE-955540
• Length: 690
• Species: Xenopus tropicalis
• Alignment Length: 510
• Identity: 167/510 - (32%)
• Similarity: 256/510 - (50%)
• Gaps: 82/510 - (16%)

  Fly    19 PASEPAADLESV-----DQKLEETHHSKFREVDRQEQEVLAEK---AAEAASQRIAQVE------ 69
            |....|..|:.:     |.|.:.. .:..|:...|:...|.:|   .....||.:.|::
 Frog   195 PTLTAATTLDHIPISAGDMKCQRP-RTLLRQQSLQQPLSLHQKHNHCQPTTSQSLGQLQLQHQPP 258

  Fly    70 --STTRSATTEAQESTTTAVPVIKKIEH--VGEVVTEVIAERTGLPTWG-VVAII---------- 119
              |::.::.|..|.:.....|.....:|  .|      |..||...:|. ||..|
 Frog   259 STSSSNTSNTRPQRTGQNRPPTSAGSKHRPAG------IRNRTNAGSWDYVVGQIRNRGLDMKSF 317

  Fly   120 ----ILVFLVVFGII----FFCV-----------------RRFLKKRRTKDGKGKKG------VD 153
                ::|..:|.|:.    |..:                 :|.....:|....|..|      .|
 Frog   318 LEGRMVVLSLVLGLSEQDDFANIPDLQTNGSQQNQNTQGDKRLQTGGKTTSASGVPGQGQSEDPD 382

  Fly   154 MKSVQ------LLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVT 212
            .|:.|      |:.|...|     |..|:..::|.|..|....:.|||:.|.:.|:|..::|.|.
 Frog   383 RKTDQHASVSDLVNSLTSE-----MLMLSPGSDEDDGHDTSGRENLGRIQFSVGYNFQESTLTVK 442

  Fly   213 VIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLV 277
            :::|:||||.|..|||||:||:|||||||.|.||||.||.|:|.:||||.|:..||...:.:.|.
 Frog   443 ILKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLY 507

  Fly   278 FAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSV-EGEGGQEKLGDICFSLRYVPTAGK 341
            ..:.|:||||::|.||||.:||...||.|....|::|... :|.|.:   |::..||.|.|:...
 Frog   508 LQVLDYDRFSRNDPIGEVSIPLNKTDLTQMQTFWKELKPCSDGSGSR---GELLLSLCYNPSTNA 569

  Fly   342 LTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQ 406
            :.|.|::|:|||.||:||.||||||:.:|...||::||||.:.|..|||.:||||.|::|.|:::
 Frog   570 IIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVVMKRCLNPIFNESFIFDIPTEKLR 634

  Fly   407 KICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLK 461
            :..:::||:|.|::..::.||:..|.......|::||.||::.||..:||||.||
 Frog   635 ETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMISHPRTAVAQWHQLK 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	28/156 (18%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	62/123 (50%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	57/134 (43%)
syt7	XP_031756132.1	C2A_Synaptotagmin-7	422..546	CDD:176032	62/123 (50%)
		C2B_Synaptotagmin-7	554..689	CDD:176050	57/137 (42%)