Protein Alignment Syt1 and syt3

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001186849.1
• Gene: syt3 / 779540
• XenbaseID: XB-GENE-956378
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 449
• Identity: 165/449 - (36%)
• Similarity: 250/449 - (55%)
• Gaps: 45/449 - (10%)

  Fly    38 HHSKFREV--DRQE-QEVLAEKA---AEAASQRIAQVESTTRSATTEAQESTTTAVPVIKKIEHV 96
            |||.:.::  ||.| ...:.|::   .::..:...::..|:.....::|....:.:|..:..:.|
 Frog   105 HHSHYGDLLADRVELGPEMPERSYLDMDSYPETNIKISQTSPDIPVDSQPPKESQIPYAQSHQQV 169

  Fly    97 GEVVTEVIAERTGLPT-------WGVVAIIILVFLVVFGIIFFCVRRFLKKRRTKDGKGKKGVDM 154
            ..:....:|.....|.       :..:.                 |...::..:.|..|.  ||.
 Frog   170 ANIAPANVAPANVAPANVAPANRYSTLP-----------------RPMTQQLSSPDFSGH--VDE 215

  Fly   155 KSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEEL 219
            |..|.....   :::|   ||.:......|..||.....||::|.|.|.:||..|.|.:::|.||
 Frog   216 KPEQATSIG---QIKP---ELYKQRSADAEMKKQEATSCGRISFILRYAYNSEQLVVKILKALEL 274

  Fly   220 PALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFD 284
            ||.|..|.||||||:|||||:||||:||||||||:|:|||||.| ::|:.:..|:.|.|:|:|||
 Frog   275 PAKDANGFSDPYVKMYLLPDRKKKFQTKVHRKTLNPIFNETFHF-NVPFNELQNRKLHFSIYDFD 338

  Fly   285 RFSKHDQIGEVKVPLCTIDLAQTIEE---WRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVI 346
            |||:||.||:|.:. ..::.:...:|   |||::....|  :..||:|.|||.|:||||:||..|
 Frog   339 RFSRHDLIGQVVLD-NLLEFSNATDETPIWRDILEASSE--KADLGEINFSLCYLPTAGRLTATI 400

  Fly   347 LEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLV 411
            ::|.|||.||:.|.||||||.:::..|:||||:||||||.||||.|||:..|::|.|.:..:.|.
 Frog   401 IKATNLKAMDLTGFSDPYVKASLICEGRRLKKRKTSIKKNTLNPTYNEALVFDIPNENMDHVSLT 465

  Fly   412 VTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETDEIL 470
            :.|:|||.||.:|.||.|.:|.........||::|||:||:||..||.|.:.:..:..:
 Frog   466 IAVMDYDCIGHNEVIGMCRVGSDADMQGREHWNEMLANPRKPIEHWHQLVEEKALNSFM 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	13/105 (12%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	66/126 (52%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	71/134 (53%)
syt3	NP_001186849.1	C2A_Synaptotagmin-1-5-6-9-10	248..372	CDD:176031	66/125 (53%)
		C2B_Synaptotagmin-3-5-6-9-10	381..514	CDD:176048	70/132 (53%)