DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt1 and Pla2g4d

DIOPT Version :9

Sequence 1:	NP_523460.2	Gene:	Syt1 / 33473	FlyBaseID:	FBgn0004242	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	XP_001080051.2	Gene:	Pla2g4d / 691905	RGDID:	1593372	Length:	825	Species:	Rattus norvegicus

Alignment Length:	151	Identity:	42/151 - (27%)
Similarity:	74/151 - (49%)	Gaps:	10/151 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 LAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMN 273
            |.|.:::|..||..|:...:||||.:.|.....:||:|:....:.:||:||||:|  |..:...|
  Rat    33 LTVKILEARSLPRADLLSKADPYVTLRLPTASGRKFKTQTVTNSSNPVWNETFSF--LIQSQVKN 95

  Fly   274 KTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYV-- 336
             .|...::|.|..:|.|...::...:..|...|.:::   ..|:..:|.:|.  |:.|.:...
  Rat    96 -ILELTVYDEDLITKDDICFKISYDISEILPGQLVQK---TFSLNPQGPEEL--DVEFLVERTCD 154

  Fly   337 PTAGKLTVVILEAKNLKKMDV 357
            |....:|..:|.|:.|..:||
  Rat   155 PPENLITNNVLVARELSHLDV 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	30/106 (28%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	9/34 (26%)
Pla2g4d	XP_001080051.2	C2_cPLA2	32..151	CDD:176001	35/125 (28%)
		PLAc	267..758	CDD:214474
		Patatin_and_cPLA2	278..814	CDD:299702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900