Protein Alignment Syt1 and Syt4

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_113881.1
• Gene: Syt4 / 64440
• RGDID: 68397
• Length: 425
• Species: Rattus norvegicus
• Alignment Length: 427
• Identity: 154/427 - (36%)
• Similarity: 216/427 - (50%)
• Gaps: 70/427 - (16%)

  Fly   100 VTEVIAERTGLPTWGVVAIIILVFLVVFGIIFF----CVRRFLKKRRTKDGK---GKKGVD---- 153
            :|....|...:||   |..|...|.:||.:..|    |.||..|..:|...|   ..||||
  Rat     4 ITTSRVEFDEIPT---VVGIFSAFGLVFTVSLFAWICCQRRSAKSNKTPPYKFVHVLKGVDIYPE 65

  Fly   154 -MKSVQLLGSAYKE---------------------------KVQP------DMEELT-----ENA 179
             :.|.:..|...|.                           |..|      |:|.:|     |..
  Rat    66 NLSSKKKFGGDDKSEAKRKAALPNLSLHLDLEKRDLNGNFPKTNPKAGSSSDLENVTPKLFPETE 130

  Fly   180 EEG------------DEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALD-MGGTSDPY 231
            :|.            ..|:||  :|||.|...|||:|...:..|.:.:|:.|||:| ...|||||
  Rat   131 KEAVSPESLKSSTSLTSEEKQ--EKLGTLFLSLEYNFEKKAFVVNIKEAQGLPAMDEQSMTSDPY 193

  Fly   232 VKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVK 296
            :|:.:||:||.|.:|:|.||||.|||:|||||..:||......:|.|.:..|||||:.|.||||.
  Rat   194 IKMTILPEKKHKVKTRVLRKTLDPVFDETFTFYGVPYPHIQELSLHFTVLSFDRFSRDDVIGEVL 258

  Fly   297 VPLCTIDLAQ-TIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGL 360
            |||..|:|:. .:...|:::....:....: |::..||.|..|...||||:|:|::|.|.||.||
  Rat   259 VPLSGIELSDGKMLMTREIIKRNAKKSSGR-GELLVSLCYQSTTNTLTVVVLKARHLPKSDVSGL 322

  Fly   361 SDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEP 425
            ||||||:.:....||:.||||.:||||.|..:||.|.|::|.|.:::|.:...|:|.:|...:|.
  Rat   323 SDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCESLEEISVEFLVLDSERGSRNEV 387

  Fly   426 IGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKD 462
            |||.:||....|:...||.::...|||.||:||.|.|
  Rat   388 IGRLVLGATAEGSGGGHWKEICDFPRRQIAKWHMLCD 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	11/39 (28%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	59/125 (47%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	60/134 (45%)
Syt4	NP_113881.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..121		4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..147		2/20 (10%)
		C2A_Synaptotagmin-4-11	153..279	CDD:176034	59/125 (47%)
		C2B_Synaptotagmin-4	288..423	CDD:176049	60/135 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820