Protein Alignment Syt1 and Syt9

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_068689.2
• Gene: Syt9 / 60510
• MGIID: 1926373
• Length: 491
• Species: Mus musculus
• Alignment Length: 308
• Identity: 145/308 - (47%)
• Similarity: 207/308 - (67%)
• Gaps: 12/308 - (3%)

  Fly   158 QLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPAL 222
            ||.|..   :::|::.:  :.:.:.|:..:.:.:..|:|||.|:||.:...|.|.:.:|..|||.
Mouse   191 QLTGIG---RIKPELYK--QRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAK 250

  Fly   223 DMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFS 287
            |..||||||||:|||||:|.|.:||||||||:|||:|.|.| .:.|.|...:.|.|:::||||||
Mouse   251 DFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLF-PVHYNDLEARKLHFSVYDFDRFS 314

  Fly   288 KHDQIGEVKVPLCTIDLAQTIEE---WRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEA 349
            :||.||:|.|. ...|||....|   |:|:..|..:  ...||::.|||.|:||||:||:.|::|
Mouse   315 RHDLIGQVVVD-HFFDLADFPRECILWKDIEYVTND--NVDLGELMFSLCYLPTAGRLTITIIKA 376

  Fly   350 KNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTV 414
            :|||.||:.|.||||||:::|.:|:||||:|||.|:.||||.|||:..|:||.|.|.:|.|.:.|
Mouse   377 RNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAV 441

  Fly   415 VDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKD 462
            :||||:|.:|.||.|.:|.........|||:||:.||:|||.||:|.:
Mouse   442 MDYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLME 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	2/2 (100%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	65/126 (52%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	73/134 (54%)
Syt9	NP_068689.2	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	9..31
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..147
		C2	221..345	CDD:472691	65/125 (52%)
		C2B_Synaptotagmin-3-5-6-9-10	354..487	CDD:176048	72/132 (55%)