Protein Alignment Syt1 and syt2a

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_696277.2
• Gene: syt2a / 567877
• ZFINID: ZDB-GENE-060503-315
• Length: 430
• Species: Danio rerio
• Alignment Length: 425
• Identity: 230/425 - (54%)
• Similarity: 304/425 - (71%)
• Gaps: 12/425 - (2%)

  Fly    52 VLAEKAAEAASQRIAQVESTTR--SATTEAQESTTTAVPVIKKIEHVGEVVTEVIAE--RTGLPT 112
            ||.:|.|...........:.|.  :.:|.|..||....||.|. :..|::..:.:.|  :..||.
Zfish     5 VLKKKPAAMVGPEPTGASALTMAPAVSTPADNSTEHQGPVSKN-DVFGDIKNKFLNEMDKLPLPP 68

  Fly   113 WGVVAIIILVFLVVFGIIFFCVRR-FLKKRRTKDG-KGKKGVDMKSVQLLGSAYKEKVQPDMEEL 175
            |.::||.|:..:::....|..|:: .|||::.|.| |||..:.||:::   ...|::...|.|::
Zfish    69 WAIIAIAIVAVVLILTCCFCIVKKTCLKKKKGKKGKKGKGDMGMKNMK---GGEKQEEDDDEEDI 130

  Fly   176 TENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDK 240
            .....|..||:.:.::|||:|.|.|:|||:::.|.|.::||.:|.::|.||||||||||::||||
Zfish   131 DMGITEEKEEEPKEKEKLGKLQFSLDYDFSASQLTVGILQAADLLSMDSGGTSDPYVKVFILPDK 195

  Fly   241 KKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLA 305
            |||::||||:|||:|||||||.|| :|:.:...||||.:::|||||||||.|||||:|:.|:|||
Zfish   196 KKKYDTKVHKKTLNPVFNETFHFK-IPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLA 259

  Fly   306 QTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIM 370
            |.||:||||.|.|.| ..|||||||.||||||||||||:.||||||||||||||||||||||.::
Zfish   260 QPIEQWRDLDSAEKE-EPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLL 323

  Fly   371 QNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMG 435
            |||||||||||::||.|||||||||||||:|.:|:|||..|:||:|||:||.::.||:..:|...
Zfish   324 QNGKRLKKKKTTVKKNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIGKIWVGSKA 388

  Fly   436 TGTELRHWSDMLASPRRPIAQWHTLKDPEETDEIL 470
            .||||||||||||:|||||||||.||..||.|..|
Zfish   389 QGTELRHWSDMLANPRRPIAQWHPLKPEEEVDATL 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	28/104 (27%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	79/123 (64%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	102/134 (76%)
syt2a	XP_696277.2	Syt2_N	5..>94	CDD:409249	22/89 (25%)
		C2A_Synaptotagmin-1-5-6-9-10	148..270	CDD:176031	78/122 (64%)
		C2B_Synaptotagmin-1	279..414	CDD:176047	102/134 (76%)