Protein Alignment Syt1 and si:ch211-266g18.6

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_005169912.1
• Gene: si:ch211-266g18.6 / 565707
• ZFINID: ZDB-GENE-131121-599
• Length: 1009
• Species: Danio rerio
• Alignment Length: 513
• Identity: 113/513 - (22%)
• Similarity: 198/513 - (38%)
• Gaps: 132/513 - (25%)

  Fly    12 KPEAEPAPASEPAADLESVDQKLEETHHSKFREVDRQE--QEVLAEKAAEAASQRIAQVES-TTR 73
            |...||...:.|:.|:....|...|..    .:||..|  .:||....|.|...|...::: |.:
Zfish   534 KSVPEPIKPAHPSDDVAGFGQDSSEIK----VDVDSAETKSDVLLNVLARAQKTRPPVLQNITNQ 594

  Fly    74 SATTEAQESTTTAV---------PVIKKIEHVGEVVTEVIAER---------------------- 107
            ....|..:.|..::         |...|....|.:|.|.:.:.
Zfish   595 EPNLEGTDDTVPSIVIVPSESPDPAEMKGNKRGALVLEALLQSSTAKNPSYIADAWEDEGVNSDD 659

  Fly   108 --TGLPTWGVVAIIILVFLVVFGIIFFCVRRFLKKRRTKDGKGKKGVDMKSVQL------LGSAY 164
              |.|.::|                             .|...:||....::.|      |.|.|
Zfish   660 DDTSLSSYG-----------------------------SDLSSRKGFSASALSLTDRTGSLLSVY 695

  Fly   165 KEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELP-ALDMGGTS 228
                             .|..|..:.:..|.:.|.:.|. ....|.:.:.|.::|. |......:
Zfish   696 -----------------SDAGDFGTVEVQGSVEFAVMYS-PVGELIIMIEQCQDLAIANPRKQRT 742

  Fly   229 DPYVKVYLLPDK--KKKFETKVHRKTLSPVFNETFTFK----SLPYADAMNKTLVFAIFDFDRFS 287
            |||||.||.|||  :.|.:|.:.::|::|||.|:..:|    .||     .|:|..:::..|...
Zfish   743 DPYVKTYLYPDKSRRSKRKTTIKKRTVNPVFVESLRYKVNREELP-----EKSLNLSVWHNDSRG 802

  Fly   288 KHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQ--EKLGDICFSLRYVPTA---------GK 341
            ::..:|:|::...|.|.......|.:|.....|..:  |..|.:..||:|||:|         |:
Zfish   803 RNVFLGQVELSFRTWDWGHEALTWYNLQPKTSENAETKESNGLLSVSLKYVPSASTGGSKSSTGE 867

  Fly   342 LTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFE--Q 404
            :.|.:.|||.|:::...|: |.:||..|:.:.::..::||.:.|.|.:|.||.:..:: .|:  :
Zfish   868 IHVWLREAKELRRLKPQGV-DSFVKCYILPDTRKKSRQKTRVVKKTQDPVYNHAMVYD-GFKTGE 930

  Fly   405 IQKICLVVTVVDYD------------RIGTSEPIGRCILGCMGTGTELRHWSDMLASP 450
            :.:.|..:||.|::            .:||.:..|:.:........|::.|..|||||
Zfish   931 VTEACCELTVWDHNTLANQFLGGVRLSLGTGQSYGKKVDWMDSVDEEVQIWKRMLASP 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	16/138 (12%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	36/130 (28%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	40/148 (27%)
si:ch211-266g18.6	XP_005169912.1	C2A_SLP-1_2	707..830	CDD:176039	35/128 (27%)
		C2B_SLP_1-2-3-4	843..999	CDD:175987	40/148 (27%)