Protein Alignment Syt1 and syt10

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_017210538.3
• Gene: syt10 / 564226
• ZFINID: ZDB-GENE-041210-297
• Length: 566
• Species: Danio rerio
• Alignment Length: 495
• Identity: 163/495 - (32%)
• Similarity: 264/495 - (53%)
• Gaps: 97/495 - (19%)

  Fly     7 SETDAKP-----EAEPAPASEPAADLESVDQKLEETHHSKFREVDRQEQEVLAEKAAEAASQRIA 66
            |..|:.|     ||.|||.                       .|.|........||...|.::.:
Zfish   103 SNADSCPPGVLLEAPPAPP-----------------------PVSRSVSPYAEAKAVGVAGRQPS 144

  Fly    67 QV----ESTTRSATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVF 127
            |:    |...:....|.:.:..::|.:::....:.:...::.||
Zfish   145 QIQHEDEEDKKWKVPEVKVNGRSSVKILEAAMKISQTSPDIPAE--------------------- 188

  Fly   128 GIIFFCVRRFLKKRRTKDGKGKK-----------------------------GVDMKSVQLLGSA 163
                  |::.|:.|.:|..|.::                             .:|...|:...:.
Zfish   189 ------VQQALRDRLSKQAKIQRQTTEPTSSSRHNSFRRHLPRQMNVTSVDFTMDTLPVRQSSAV 247

  Fly   164 YKEKVQPDM-EELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGT 227
            ...:::|:: ::.:.::|||.:|..::   .|:|:|.|.||:...:|.|.:::|.:|||.|..||
Zfish   248 SIGRIKPELYKQKSVDSEEGTKEPVET---CGKLSFALSYDYEEQALVVRILKALDLPAKDFTGT 309

  Fly   228 SDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQI 292
            ||||||:||||::||||:|:||||||:|.|:|.|.| .:.|::..|:.|.|:::|||||:.||.|
Zfish   310 SDPYVKIYLLPERKKKFQTRVHRKTLNPTFDEDFRF-PVEYSELCNRKLHFSVYDFDRFTSHDMI 373

  Fly   293 GEVKVP-LCTI-DLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKM 355
            |||.|. |..: ||::....|:|:::...|  ...||:|.:||.|:||||::|:.:::.:|||.|
Zfish   374 GEVVVDNLFELSDLSREAVVWKDILAATTE--SVDLGEIMYSLCYLPTAGRMTLTVIKCRNLKAM 436

  Fly   356 DVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRI 420
            |:.|.||||||:|::.:|:||||:||:.||.||||.|||:..|::|.|.::::.|.:||:||||:
Zfish   437 DITGYSDPYVKVALICDGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVEQVSLSITVMDYDRV 501

  Fly   421 GTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 460
            |.:|.||.|..|....|....||::|||.||:||..||.|
Zfish   502 GHNEVIGVCRAGPDAEGLGRDHWNEMLAYPRKPITHWHAL 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	13/131 (10%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	62/125 (50%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	69/135 (51%)
syt10	XP_017210538.3	C2A_Synaptotagmin-1-5-6-9-10	274..399	CDD:176031	62/128 (48%)
		C2B_Synaptotagmin-3-5-6-9-10	408..541	CDD:176048	67/132 (51%)