Protein Alignment Syt1 and Syt10

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_061273.1
• Gene: Syt10 / 54526
• MGIID: 1859546
• Length: 523
• Species: Mus musculus
• Alignment Length: 475
• Identity: 171/475 - (36%)
• Similarity: 248/475 - (52%)
• Gaps: 97/475 - (20%)

  Fly     3 PNAKSETDAKPEAE----PAP-ASEPA-------ADLESVDQKLEETHHSKFREVDRQEQEVLAE 55
            |....||:.|.|.|    ||| |.|||       .|:.:..|...:.|..|...|.||..|..:.
Mouse   104 PTEVFETEEKKEVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTEPTSS 168

  Fly    56 KAAEAASQRIAQ---VESTTRSATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVA 117
            ....:..:.:.:   |.|...|..||         |::::    ||..|.:..
Mouse   169 SRHNSFRRHLPRQMNVSSVDFSVGTE---------PILQR----GETRTSIGR------------ 208

  Fly   118 IIILVFLVVFGIIFFCVRRFLKKRRTKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEELTENAEEG 182
                            ::..|.|:::.|.:|.:..|:|:
Mouse   209 ----------------IKPELYKQKSVDSEGNRKDDVKT-------------------------- 231

  Fly   183 DEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETK 247
                      .|:|||.|:||:.:..|.|.:|:|.:|||.|..||||||||:|||||:||||:|:
Mouse   232 ----------CGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTR 286

  Fly   248 VHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVP-LCTI-DLAQTIEE 310
            ||||||:|:|:|.|.| .:.|....|:.|.|:|:||||||:||.||||.:. |..: ||::....
Mouse   287 VHRKTLNPLFDELFQF-PVVYDQLSNRKLHFSIYDFDRFSRHDMIGEVILDNLFEVSDLSREATV 350

  Fly   311 WRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKR 375
            |:|:.....|  ...||:|.|||.|:||||::|:.:::.:|||.||:.|.||||||:::|..|:|
Mouse   351 WKDIHCATTE--SIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413

  Fly   376 LKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTEL 440
            |||:||:.||.||||.|||:..|::|.|.:.::.|.:.|:||||:|.:|.||.|..|....|...
Mouse   414 LKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGR 478

  Fly   441 RHWSDMLASPRRPIAQWHTL 460
            .||::|||..|:||..||.|
Mouse   479 DHWNEMLAYHRKPITHWHPL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	29/145 (20%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	66/125 (53%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	68/135 (50%)
Syt10	NP_061273.1	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	13..35
		C2A_Synaptotagmin-1-5-6-9-10	231..356	CDD:176031	66/161 (41%)
		C2B_Synaptotagmin-3-5-6-9-10	365..498	CDD:176048	66/132 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394604at33208
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820