Protein Alignment Syt1 and syt4

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001164985.1
• Gene: syt4 / 447980
• XenbaseID: XB-GENE-5963049
• Length: 424
• Species: Xenopus tropicalis
• Alignment Length: 414
• Identity: 152/414 - (36%)
• Similarity: 209/414 - (50%)
• Gaps: 74/414 - (17%)

  Fly   114 GVVAIIILVFLVVFGIIFFCVRRFLKKRRTK------------------DGKGKKGVDMK----- 155
            |:|:...|||.|.......|.|:..|...|.                  :.|.|.|.|.|
 Frog    19 GLVSGFGLVFTVSLFSWICCQRKSAKSNTTPPYKFVHVLKGVDIYPESLNSKKKFGADEKTELAP 83

  Fly   156 -------SVQL----------LGSAYKEKVQPDMEELTENAEEGDEEDKQS-------------- 189
                   |:.|          ...|.|.:..||:|:.::  .:..|:||.|
 Frog    84 KSLISKTSLHLDLEKRDLNGNFPKANKVRSSPDLEDFSQ--PQLPEKDKDSVSPESVKSNASVVS 146

  Fly   190 ---EQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALD-MGGTSDPYVKVYLLPDKKKKFETKVHR 250
               :.|||.|.|.|||:|...:..|.:.:|..|||:| ...|||||:|:.:||:||.|.:|:|.|
 Frog   147 LDKQDKLGTLFFALEYNFEKKAFVVNIKEARSLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLR 211

  Fly   251 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLV 315
            |||.|.|:|||||..:||:...:..|.|.|..|||||:.|.||||..||..|:|:    :.|.|:
 Frog   212 KTLDPAFDETFTFYGIPYSQVQDLVLHFIILSFDRFSRDDVIGEVSFPLSGIELS----DGRVLM 272

  Fly   316 -------SVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNG 373
                   :|....|:   |::..||.|..|...||||:|:|::|.|.:|.||||||||:.:....
 Frog   273 NREINKRNVRKSAGR---GELLISLCYQSTTNTLTVVVLKARHLPKAEVSGLSDPYVKVNLYHAK 334

  Fly   374 KRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGT 438
            ||:.||||.:||||.|..:||.|.|::|.|.::.|.:...|:|.||...:|.|||.|||....||
 Frog   335 KRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVMDSDRGSRNEVIGRLILGSSADGT 399

  Fly   439 ELRHWSDMLASPRRPIAQWHTLKD 462
            ...||.::...|||.||:||.|.|
 Frog   400 GGEHWKEICEHPRRQIAKWHMLCD 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	17/86 (20%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	60/131 (46%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	62/134 (46%)
syt4	NP_001164985.1	C2A_Synaptotagmin-4-11	152..278	CDD:176034	60/129 (47%)
		C2B_Synaptotagmin-4	287..422	CDD:176049	62/137 (45%)