DRSC/TRiP Functional Genomics Resources

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Protein Alignment Syt1 and syt5a

DIOPT Version :10

Sequence 1:NP_523460.2 Gene:Syt1 / 33473 FlyBaseID:FBgn0004242 Length:474 Species:Drosophila melanogaster
Sequence 2:NP_001096607.3 Gene:syt5a / 436686 ZFINID:ZDB-GENE-040718-110 Length:410 Species:Danio rerio


Alignment Length:430 Identity:217/430 - (50%)
Similarity:291/430 - (67%) Gaps:47/430 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 RIAQVESTTRSATTEAQESTTTAVPVIKKIEH---------------VGEVVTEVIAERTGLPTW 113
            |:|.::...|.| .|::|....|.|......|               :|.:....|.    :|.|
Zfish     2 RLASMQHRGRRA-AESEEEPNRAPPPPPPPSHHSHNFVNMKNKFFNELGHLPNHKIR----MPMW 61

  Fly   114 GVVAIIILVFLVVFGIIFFCV-RRFL-KKRRTKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEELT 176
            .:.|||::| |.:.|...||: ::.| .|::||..:.:||            .:.:::.:.||  
Zfish    62 AIGAIIVVV-LALVGCFAFCIYKKCLGGKKKTKKVRERKG------------GRRRMKKEGEE-- 111

  Fly   177 ENAEEGDEEDKQSE-----QKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYL 236
               |.|:|:.|:.|     :..|:|.:.|:|:|..|.|.|.::||::|||:|:|||||||||||:
Zfish   112 ---EAGEEQPKEGEGEGEKEYYGKLEYTLDYNFTENQLIVGILQAQDLPAMDIGGTSDPYVKVYM 173

  Fly   237 LPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCT 301
            ||||||||||||.||.|.|||||||.|| :|:.|...:|||..:||||||.|||.|||:|:|:.:
Zfish   174 LPDKKKKFETKVQRKNLCPVFNETFIFK-IPFNDLAGQTLVLQVFDFDRFGKHDVIGEIKIPMNS 237

  Fly   302 IDLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVK 366
            |||.|.|.|::|||..|.| .||||||||.|||||||:|||||.|:||||||||||||||||:||
Zfish   238 IDLGQPIHEYKDLVGGEKE-EQEKLGDICISLRYVPTSGKLTVCIMEAKNLKKMDVGGLSDPFVK 301

  Fly   367 IAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCIL 431
            |.:..||||:|||||::|:.|||||:|||||||:||.||||:.:::||.|||::|:::|||:|.:
Zfish   302 IVLQHNGKRIKKKKTTVKQNTLNPYFNESFSFEIPFAQIQKVQVLITVYDYDKLGSNDPIGKCWI 366

  Fly   432 GCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETDEILK 471
            |...:|..|||||||||:||||:||||||:..||.|..||
Zfish   367 GFGASGVGLRHWSDMLANPRRPVAQWHTLQPEEEVDAALK 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Syt1NP_523460.2 Syt1_2_N 62..161 CDD:425364 27/113 (24%)
C2A_Synaptotagmin-1-5-6-9-10 192..316 CDD:176031 76/123 (62%)
C2B_Synaptotagmin-1 326..461 CDD:176047 95/134 (71%)
syt5aNP_001096607.3 None

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