Protein Alignment Syt1 and Syt4

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 413
• Identity: 139/413 - (33%)
• Similarity: 205/413 - (49%)
• Gaps: 99/413 - (23%)

  Fly   137 FLKKRRTKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQ---------- 191
            :|||..:..|.       |.:.||.....:...|..:...:.:||||...:.:||
  Fly    74 YLKKSPSPTGG-------KQMGLLSPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQQNGNQLTVVD 131

  Fly   192 -----------------------------------------------KLGRLNFKLEYDFNSNSL 209
                                                           |||.:.|||.|....|:|
  Fly   132 GNGLKHSLHNSLHHSPVETIANGSVTITLDDHSLTNGKELTVTDQYGKLGTIYFKLRYLAERNAL 196

  Fly   210 AVTVIQAEELPALDMGGTS-----------------DPYVKVYLLPDKKKKFETKVHRKTLSPVF 257
            .|::|:...||.  .||:|                 |||||:.|||||:.|.:|:|.|.|.:||:
  Fly   197 MVSIIRCRGLPC--KGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNTRNPVY 259

  Fly   258 NETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGG 322
            :|.|||..|...|..|.:|.|.|..|||:|:.|.||||..||.:|::....:|   .:|:..|..
  Fly   260 DEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKE---ALSISKEIQ 321

  Fly   323 QEKL-------GDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKK 380
            ...|       |::..||.:.|.||:||||:|:|:||.:|||.||:||||||.::.||:|:.|||
  Fly   322 PRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKK 386

  Fly   381 TSIKKCTLNPYYNESFSFEVPFEQ-----IQKICLVVTVVDYDRIGTSEPIGRCIL-GCMGTGTE 439
            |.:||.||:|.:||||:|::|..:     ::.:.|.:.::|:||:..:|.|||..| |...:.|.
  Fly   387 THVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSSTA 451

  Fly   440 LRHWSDMLASPRRPIAQWHTLKD 462
            |.||:::..||||.||:||.|.:
  Fly   452 LNHWNEVCNSPRRQIAEWHKLNE 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	6/23 (26%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	56/140 (40%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	66/147 (45%)
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	58/147 (39%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	65/140 (46%)