Protein Alignment Syt1 and syt11a

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_998625.2
• Gene: syt11a / 406769
• ZFINID: ZDB-GENE-040426-2815
• Length: 451
• Species: Danio rerio
• Alignment Length: 456
• Identity: 147/456 - (32%)
• Similarity: 218/456 - (47%)
• Gaps: 107/456 - (23%)

  Fly   104 IAERTGL-PTWGVVAII-------ILVFLVVFGIIFF--CVRRF--------------------- 137
            :||.|.| ||:.|..::       :||..|...:..:  |.||:
Zfish     1 MAEMTNLKPTYDVSPVLAGFLGAGVLVVSVTVAVFLWTCCQRRYRQMTGAYKLTSGPYDPPVDPP 65

  Fly   138 -------------------LKK-----RRTKD-------GKGKKGVDMKSVQL------------ 159
                               .||     ||:..       |:|.:..|:..|..
Zfish    66 YKFIHMLKGISIYPETLSNSKKIVRVGRRSASNSLLREWGRGSRNGDVLLVDADPECGTTHLQMN 130

  Fly   160 -----LGSAYKEKVQP------DMEELTENAEEGDEEDKQ----SEQKLGRLNFKLEYDFNSNSL 209
                 :|....|:..|      .||..:.::.|...:...    :...||.|:..::|:|...:|
Zfish   131 HLVPPVGPPRLERALPIRADYCCMESSSGSSSEAHSKTASPYSLNSPSLGTLSLAIDYNFPKKAL 195

  Fly   210 AVTVIQAEELPALD-MGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMN 273
            .||:|.|:.|||:| ..|:||||||:.:||:||.:.:|:|.||||.|||:|||||..:||:....
Zfish   196 VVTIIGAQGLPAVDEQAGSSDPYVKMTILPEKKHRVKTRVLRKTLEPVFDETFTFYGVPYSSLPE 260

  Fly   274 KTLVFAIFDFDRFSKHDQIGEVKVPLCTID-------LAQTIEEWRDLVSVEGEGGQEKLGDICF 331
            .||.|.:..||||::.|.|||..|||..:|       :.|.|.:.....        |..|::..
Zfish   261 LTLHFLVLSFDRFARDDVIGEAVVPLEGVDPSTGRAHITQQISKRNTQC--------ESRGELLV 317

  Fly   332 SLRYVPTAGKLTVVILEAKNLKKMDVGGLS-DPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNES 395
            ||.|.|...:|.||:|:||:|..||:.||| :||||:.:....||:.||||.:|||||||.:|||
Zfish   318 SLSYHPVTHRLNVVVLKAKHLPTMDITGLSGNPYVKVNVFYGRKRIAKKKTHVKKCTLNPVFNES 382

  Fly   396 FSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMG-TGTELRHWSDMLASPRRPIAQWHT 459
            |.::||.|.:..|.:...|:|:||...:|.:||.:||... ..:.:.||.::..:|||.||:||.
Zfish   383 FIYDVPAELMPDISVEFLVIDFDRTTKNEVVGRLVLGGQSPIPSGVTHWREVCDNPRRQIAKWHN 447

  Fly   460 L 460
            |
Zfish   448 L 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	11/41 (27%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	58/131 (44%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	61/137 (45%)
syt11a	NP_998625.2	C2	179..290	CDD:301316	55/110 (50%)
		C2B_Synaptotagmin-4	312..449	CDD:176049	61/137 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X85
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820