Protein Alignment Syt1 and DH11.5

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001254131.1
• Gene: DH11.5 / 3565199
• WormBaseID: WBGene00008438
• Length: 825
• Species: Caenorhabditis elegans
• Alignment Length: 386
• Identity: 83/386 - (21%)
• Similarity: 139/386 - (36%)
• Gaps: 138/386 - (35%)

  Fly   168 VQPDMEELTEN--------AEEGDEEDKQSEQKLGRLNFKLEYDFNSNS---LAVTVIQAEELPA 221
            |:.::.|..|:        .|||             :||..::.|...|   :....:...::||
 Worm   482 VEQEISEYLEHCRDASVNITEEG-------------MNFIAKHFFEYQSFMNIPHKAVHLHKVPA 533

  Fly   222 LDMGGTSDPYV----KVYLLPDKKKKF----ETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVF 278
            ...|  :||.:    |..|...|.:..    ..:|||   .|..|.|
 Worm   534 SQAG--TDPSMGWAPKNMLKAGKHQPAPGARANRVHR---DPRPNGT------------------ 575

  Fly   279 AIFDFDRFSKH------DQIGEV---KVPLCTIDL-----------AQTIEE--WRD-LVSVEGE 320
               .:.|..||      |:.||:   || .|..|.           |:|..|  :.| :::.|.|
 Worm   576 ---KYGRAGKHEHREWGDRHGELRDEKV-ACHKDAWTKFLANDDQGARTAFECDFEDRVLATEEE 636

  Fly   321 GGQEKL------------------------GDIC---FSLRYVPTAGKLTVVILEAKNLKKMDVG 358
            ..||||                        ||:|   ..|.|.||...:|..:.:||.|...:.
 Worm   637 TLQEKLCRTSPEAMNLNALYAAANKAVSCGGDVCELLTILTYAPTVQFVTTTVKKAKALPYNNA- 700

  Fly   359 GLSDPYVKIAIMQNGKRLKKKKTSIKKCTL---------------------NP---YYNESFSFE 399
                |:.:|.:.:..:.:::|:|::....:                     ||   .::|||.|.
 Worm   701 ----PFARIMLFEGRRLMEQKQTTVNPSLVHKSSVDGSKPSSSSASTSSNDNPSDVSFSESFLFH 761

  Fly   400 VPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 460
            ||..::.:..:|:.:.|:|..|..:.||.|::|.:..||...||..|:.....|:..||.:
 Worm   762 VPPTKLDRSHIVIELYDHDDEGGLQKIGHCVIGRLVDGTGNAHWIQMVRQHGLPVCMWHKI 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	32/157 (20%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	40/186 (22%)
DH11.5	NP_001254131.1	C2B_Synaptotagmin	671..822	CDD:175975	36/155 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910