Protein Alignment Syt1 and Syt14

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_006497318.1
• Gene: Syt14 / 329324
• MGIID: 2444490
• Length: 857
• Species: Mus musculus
• Alignment Length: 514
• Identity: 110/514 - (21%)
• Similarity: 199/514 - (38%)
• Gaps: 101/514 - (19%)

  Fly    22 EPAADLESVD-------QKLEETHHSKFREVDRQEQEVLAEKAAEAASQRIAQVESTTRSATTEA 79
            ||.:..||.|       :.|..||:|::..||.:::....|     ..|:.:.:.:.....:|||
Mouse   367 EPGSSSESEDEALGKYHEALSRTHNSRWPLVDSRQKSYAWE-----TRQKYSPLSAEYDGYSTEA 426

  Fly    80 QESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCVRRFLKKRRTK 144
            .......:..:::...:.|:......:.:|.|.                  ..|....:...:.:
Mouse   427 SMEDGNCIQRMRRTPPLDELQPPPYQDDSGSPH------------------LSCTPSEIGDAKCE 473

  Fly   145 ---------------DGKGKKGVDMKSVQLLGSAYKEKVQPDMEEL---TENAEEGDEE------ 185
                           ..:|..|.:.:|....|  |::.|..|...:   .:.:.:|...
Mouse   474 ISHCSNSPRCSFNKCPSEGSTGHEAESYHNKG--YEDDVPSDSTAVLSPEDMSAQGSSSQLPKPF 536

  Fly   186 DKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHR 250
            |.:.|.|.|.|:...:||.....|.|||....::|..:..|.:...|.:.|||.||::.:|.:.|
Mouse   537 DPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 601

  Fly   251 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGE-------------VKVPL--- 299
            .. .|||.|||.|..:......|..:.|.::...|..|...:||             :.:|:
Mouse   602 GP-CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILE 665

  Fly   300 -------CTIDLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMD- 356
                   |...::.:.....|..|.........:.:|...|.|..|.|:|:..:::..:.|.:.
Mouse   666 PSYNPSGCDSQVSLSEASCGDSTSSCQSLQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAA 730

  Fly   357 --------------VGG----LSDPYVKIAIMQN-GKRLKKKKTSIKKCTLNPYYNESFSFEVPF 402
                          :||    :.|.|||:.::.: |:.:.|.|||.::...||.|.|:|.|:|..
Mouse   731 NRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVAL 795

  Fly   403 EQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTG-TELRHWSDMLASPRRPIAQWHTL 460
            .|:..:.|:::|.:...:...|.||...||...:| .|||||:.|..|..:.:.:||.|
Mouse   796 FQLSDVTLILSVYNRRSMKRKEMIGWISLGLNSSGEEELRHWTAMKESKGQQVCRWHAL 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	20/120 (17%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	35/146 (24%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	44/156 (28%)
Syt14	XP_006497318.1	C2A_Synaptotagmin-14_16	543..666	CDD:176035	33/123 (27%)
		C2B_Synaptotagmin-14_16	699..855	CDD:176053	44/156 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810