Protein Alignment Syt1 and Syt16

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001351210.1
• Gene: Syt16 / 238266
• MGIID: 2673872
• Length: 654
• Species: Mus musculus
• Alignment Length: 323
• Identity: 83/323 - (25%)
• Similarity: 141/323 - (43%)
• Gaps: 56/323 - (17%)

  Fly   183 DEEDKQSEQ----------KLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLL 237
            :|:|..|.|          |.|.|:...||...:..|.||:::|:.||..|..|.:...|.:.||
Mouse   340 EEQDGTSLQVPHRLLEPISKCGDLDVIFEYRAVTQKLTVTIVRAQGLPDKDRSGVNSWQVHIVLL 404

  Fly   238 PDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQI---------- 292
            |.||::.:|.:.|.. :|||.|..||..|...|..:..:.|.::...:.::...:
Mouse   405 PSKKQRGKTNIQRGP-NPVFKEKVTFTKLEPRDVASCAVRFRLYAARKMTRERMMGEKLFCLSHL 468

  Fly   293 ---GEVKVPLCTIDLAQTIEEWRDLVSVE--------------------GEGGQEKLGDICFSLR 334
               ||:||.|       .:|...:|.|.|                    ..||   :.::...|.
Mouse   469 HPEGEMKVTL-------VLEPRSNLSSGESPLSPSVVSHSDSASSTQSLSHGG---VPELLVGLS 523

  Fly   335 YVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQ-NGKRLKKKKTSIKKCTLNPYYNESFSF 398
            |..|.|:|:|.:::..:.:.:......|.|.|:.::. .|:.:.:.||||::...||.|.|:|.|
Mouse   524 YNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVF 588

  Fly   399 EVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTG-TELRHWSDMLASPRRPIAQWHTL 460
            :|...|:..:.|::::.....:...|.||...||...:| .|..||.:|..|..:...:||||
Mouse   589 QVALFQLSDVTLMISIYSRRTMKRKEMIGWVALGQNSSGEEEQEHWEEMKESKGQQTCRWHTL 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	37/136 (27%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	38/137 (28%)
Syt16	NP_001351210.1	C2A_Synaptotagmin-14_16	359..482	CDD:176035	35/130 (27%)
		C2B_Synaptotagmin-14_16	515..652	CDD:176053	38/137 (28%)