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Protein Alignment Syt1 and SYT11

DIOPT Version :9

Sequence 1:	NP_523460.2	Gene:	Syt1 / 33473	FlyBaseID:	FBgn0004242	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	XP_016856248.1	Gene:	SYT11 / 23208	HGNCID:	19239	Length:	434	Species:	Homo sapiens

Alignment Length:	370	Identity:	142/370 - (38%)
Similarity:	212/370 - (57%)	Gaps:	51/370 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 RRFLKKRRTKDGKGKKG------VDMKSVQLL-----------GSA---------YKEKVQPDME 173
            ::.:|.||.|||.|::|      ||.....||           ||.         |.|:::..:.
Human    73 KKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPIT 137

  Fly   174 ELT-----ENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALD---MGGTSDP 230
            .||     ..:....|||..    ||.|.|.::|:|...:|.||:.:|..||.:|   .|  |||
Human   138 SLTPGESKTTSPSSPEEDVM----LGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQG--SDP 196

  Fly   231 YVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEV 295
            |:|:.:||||:.:.:|:|.||||.|||:|||||..:||:...:..|.|.:..|||||:.|.||||
Human   197 YIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV 261

  Fly   296 KVPLCTIDLAQ-TIEEWRDLVSVEGEGGQEKL--GDICFSLRYVPTAGKLTVVILEAKNLKKMDV 357
            .|||..:|.:. .::..||::.   ...|:.:  |::..||.|.|.|.::|||:|:|::|.|||:
Human   262 MVPLAGVDPSTGKVQLTRDIIK---RNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDI 323

  Fly   358 GGLS----DPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYD 418
            .|||    |||||:.:....||:.||||.:|||||||.:||||.:::|.:.:..|.:...|:|:|
Human   324 TGLSGRAPDPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFD 388

  Fly   419 RIGTSEPIGRCILGCMG-TGTELRHWSDMLASPRRPIAQWHTLKD 462
            |...:|.:||.|||... |.:...||.::..|||:|:|:||:|.:
Human   389 RTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 433

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.