Protein Alignment Syt1 and Syt4

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_033334.2
• Gene: Syt4 / 20983
• MGIID: 101759
• Length: 425
• Species: Mus musculus
• Alignment Length: 425
• Identity: 149/425 - (35%)
• Similarity: 214/425 - (50%)
• Gaps: 66/425 - (15%)

  Fly   100 VTEVIAERTGLPTWGVVAIIILVFLVVFGIIFF----CVRRFLKKRRT----------------- 143
            :|....|...:||   |..|...|.:||.:..|    |.||..|..:|
Mouse     4 ITTSRVEFDEIPT---VVGIFSAFGLVFTVSLFAWICCQRRSAKSNKTPPYKFVHVLKGVDIYPE 65

  Fly   144 -------------KDGKGKKG-------VDMKSVQLLGSAYK-----------EKVQPDMEELTE 177
                         .:.|||..       :|::...|.|:..|           |.|.|.:...||
Mouse    66 NLSSKKKFGGDDKSEVKGKAALPNLSLHLDLEKRDLNGNFPKANPKAGSSSDLENVTPKLFTETE 130

  Fly   178 NAEEGDEEDKQS--------EQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALD-MGGTSDPYVK 233
            ......|..|.|        ::|||.|...|||:|...:..|.:.:|:.|||:| ...|||||:|
Mouse   131 KEANSPESLKSSTSLTSEEKQEKLGTLFLSLEYNFEKKAFVVNIKEAQGLPAMDEQSMTSDPYIK 195

  Fly   234 VYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVP 298
            :.:||:||.:.:|:|.||||.|||:|||||..:||......:|.|.:..|||||:.|.||||.:|
Mouse   196 MTILPEKKHRVKTRVLRKTLDPVFDETFTFYGIPYPHIQELSLHFTVLSFDRFSRDDVIGEVLIP 260

  Fly   299 LCTIDLAQ-TIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD 362
            |..|:|:. .:...|:::....:....: |::..||.|..|...||||:|:|::|.|.||.||||
Mouse   261 LSGIELSDGKMLMTREIIKRNAKKSSGR-GELLVSLCYQSTTNTLTVVVLKARHLPKSDVSGLSD 324

  Fly   363 PYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIG 427
            ||||:.:....||:.||||.:||||.|..:||.|.|::|.|.:::|.:...|:|.:|...:|.||
Mouse   325 PYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCESLEEISVEFLVLDSERGSRNEVIG 389

  Fly   428 RCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKD 462
            |.:||....|:...||.::...|||.||:||.|.|
Mouse   390 RLVLGATAEGSGGGHWKEICDFPRRQIAKWHMLCD 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	11/39 (28%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	57/125 (46%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	60/134 (45%)
Syt4	NP_033334.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..147		5/19 (26%)
		C2A_Synaptotagmin-4-11	153..279	CDD:176034	57/125 (46%)
		C2B_Synaptotagmin-4	288..423	CDD:176049	60/135 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820