Protein Alignment Syt1 and Rph3a

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_011246487.1
• Gene: Rph3a / 19894
• MGIID: 102788
• Length: 684
• Species: Mus musculus
• Alignment Length: 319
• Identity: 109/319 - (34%)
• Similarity: 158/319 - (49%)
• Gaps: 27/319 - (8%)

  Fly   169 QPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVK 233
            ||...|  |..||.:..|......||.|.|.|.||.::::|..|:|:|:.|..:|..|.:|||||
Mouse   361 QPPPAE--EEEEEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVK 423

  Fly   234 VYLLP--DKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVK 296
            ::|||  .|..|..||..|.|.:||:|||..:..:...|...|||..::.|.|:|..::.|||.:
Mouse   424 LHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETR 488

  Fly   297 VPLCTIDLAQ------------------TIEEWRDLVSVEGE-----GGQEKLGDICFSLRYVPT 338
            ..|..:...|                  |....|.:...|.|     |..|:.|.|..||.|...
Mouse   489 FSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQ 553

  Fly   339 AGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFE 403
            .|.|.|.|:...:|..||..|.|||:||:.:..:..:..|.||.|||.||||.:||.|.:::...
Mouse   554 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHS 618

  Fly   404 QIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKD 462
            .:.|..|.::|.|||...:::.||.|.||....|..|:||.:.|.:..:.|.:||.|::
Mouse   619 DLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQN 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	47/143 (33%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	50/134 (37%)
Rph3a	XP_011246487.1	FYVE_RP3A	88..168	CDD:277301
		PRK07764	<175..352	CDD:236090
		C2A_Rabphilin_Doc2	383..506	CDD:176000	45/122 (37%)
		C2B_Rabphilin_Doc2	543..675	CDD:176030	49/131 (37%)