Protein Alignment Syt1 and snt-2

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_497261.2
• Gene: snt-2 / 185680
• WormBaseID: WBGene00004922
• Length: 369
• Species: Caenorhabditis elegans
• Alignment Length: 372
• Identity: 160/372 - (43%)
• Similarity: 231/372 - (62%)
• Gaps: 25/372 - (6%)

  Fly   113 WGVVAIIILVFLVVFGIIFFC--VRRFLKKRRTKDG--KGKKGVDM--KSVQLLGSAYKEKVQPD 171
            |...||   |...||.|:..|  :||.:.   |.:|  ...|.||:  .:|.:| |:....|||.
 Worm     2 WATGAI---VCSPVFRILSTCCPIRRGVP---TSNGYHPRPKHVDIGNGAVPIL-SSKPITVQPT 59

  Fly   172 MEELTENAEEGDEEDKQSE---QKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVK 233
            ..:..|....|......|.   ::.|.::|::||||..:.|:||::.|.:|||:|..|.||||||
 Worm    60 NSDYYEPVNNGTLPLSSSGALIKQYGNIHFRVEYDFEQSKLSVTIVSASDLPAMDRNGMSDPYVK 124

  Fly   234 VYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVP 298
            ||:||::|:||||::.|.||:|.:||||.| |:|:.:..:|||:..::|:||.||.|::|::.||
 Worm   125 VYVLPERKQKFETRIIRNTLNPTYNETFQF-SIPFNELHSKTLMLVVYDYDRLSKDDKMGQLSVP 188

  Fly   299 LCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD 362
            |.:||...|.:..|.|...|.:..:| :|||||||.||.|..|.:|:.|:||:|||||||||.||
 Worm   189 LESIDFGITTDIERPLQKPEKDDEKECRLGDICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSD 253

  Fly   363 PYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIG 427
            |||||.:....|.|.|||||.|..||||||||||.|::....|:|:.|:|:|.|||::..::.||
 Worm   254 PYVKIYLHHGRKLLSKKKTSRKYKTLNPYYNESFQFKIEPHMIEKVHLIVSVWDYDKMSKNDFIG 318

  Fly   428 RCILGCMGTG-TELRH-----WSDMLASPRRPIAQWHTLKDPEETDE 468
            ...||..... .::.|     |::|:.| |||:.|||||::..|.::
 Worm   319 EVTLGSKHLNLPQITHACSEQWAEMMTS-RRPVVQWHTLQERMEKEK 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	16/53 (30%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	59/123 (48%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	73/140 (52%)
snt-2	NP_497261.2	C2	85..206	CDD:472691	59/121 (49%)
		C2B_Synaptotagmin-1	217..357	CDD:176047	73/140 (52%)