DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt1 and Y48G8AR.2

DIOPT Version :9

Sequence 1:	NP_523460.2	Gene:	Syt1 / 33473	FlyBaseID:	FBgn0004242	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_490838.3	Gene:	Y48G8AR.2 / 171702	WormBaseID:	WBGene00021693	Length:	339	Species:	Caenorhabditis elegans

Alignment Length:	114	Identity:	25/114 - (21%)
Similarity:	42/114 - (36%)	Gaps:	36/114 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 KVPLCTI-----DLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKM 355
            |..|||:     :|:....||     |:|....||            |:.:|..|:..::....:
Worm   139 KYSLCTVCYSERELSAAKNEW-----VQGSDEAEK------------TSEQLLNVMKSSEKRNSV 186

  Fly   356 DVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQ 404
            .:.. :.|.||      ||...|:..::      |....|: ..||.|:
Worm   187 QIPA-TPPAVK------GKAPYKRNLTL------PAIQTSY-LSVPDEE 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	7/24 (29%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	14/79 (18%)
Y48G8AR.2	NP_490838.3	PHD_SF	15..159	CDD:389947	5/19 (26%)
Y48G8AR.2	NP_490838.3	FYVE_Slp3_4_5	95..148	CDD:277286	4/8 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900