Protein Alignment Syt1 and SYT9

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_011518202.1
• Gene: SYT9 / 143425
• HGNCID: 19265
• Length: 567
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 148/314 - (47%)
• Similarity: 212/314 - (67%)
• Gaps: 12/314 - (3%)

  Fly   155 KSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEEL 219
            |..||.|..   :::|::.:  :.:.:.|:..:.:.:..|:|||.|:||.:...|.|.:.:|..|
Human   188 KQEQLTGIG---RIKPELYK--QRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNL 247

  Fly   220 PALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFD 284
            ||.|..||||||||:|||||:|.|.:||||||||:|||:|.|.| .:||.|...:.|.|:::|||
Human   248 PAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLF-PVPYNDLEARKLHFSVYDFD 311

  Fly   285 RFSKHDQIGEVKVPLCTIDLAQTIEE---WRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVI 346
            |||:||.||:|.|. ..:|||....|   |:|:..|..:  ...||::.|||.|:||||:||:.|
Human   312 RFSRHDLIGQVVVD-HFLDLADFPRECILWKDIEYVTND--NVDLGELMFSLCYLPTAGRLTITI 373

  Fly   347 LEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLV 411
            ::|:|||.||:.|.||||||:::|.:|:||||:|||.|:.||||.|||:..|:||.|.|.:|.|.
Human   374 IKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLS 438

  Fly   412 VTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEE 465
            :.|:||||:|.:|.||.|.:|.........|||:||:.||:|||.||:|.:.:|
Human   439 IAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEIKE 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	3/5 (60%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	66/126 (52%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	73/134 (54%)
SYT9	XP_011518202.1	C2	221..345	CDD:472691	66/125 (53%)
		C2B_Synaptotagmin-3-5-6-9-10	354..487	CDD:176048	72/132 (55%)