Protein Alignment Syt1 and LOC1275499

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_061516541.1
• Gene: LOC1275499 / 1275499
• VectorBaseID: AGAMI1_008322
• Length: 514
• Species: Anopheles gambiae
• Alignment Length: 462
• Identity: 139/462 - (30%)
• Similarity: 225/462 - (48%)
• Gaps: 63/462 - (13%)

  Fly     5 AKSETDAKPEAEPAPASEPAADLESVDQKLEETHHSKFREVDRQEQEVLAEKAAEAASQRIAQVE 69
            |.....|:.:..|..||          |.|.....|:.:.:|..::|...|.:.::|.
Mosquito    96 AHGSPQARADHPPFWAS----------QGLYRKSDSRGQLIDTSDEETTGEDSGDSAC------- 143

  Fly    70 STTRSATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCV 134
            |::||...    :.:.||.:....:|| .:||...|:    ||..:||       .|.|
Mosquito   144 SSSRSVIA----APSGAVAIASTGKHV-VLVTSSPAK----PTTSMVA-------TVAG------ 186

  Fly   135 RRFLKKRRTKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFK 199
                ..|.:..|.....||.          .:..:.||.:..........::...|...|.::..
Mosquito   187 ----GSRGSATGATASKVDT----------SQGTKIDMLDSASTCSTVSRDELGGEDARGAIHLT 237

  Fly   200 LEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFK 264
            |.||..:..|.|.:::|::|...|..||:|||.|:.||||:...::|::|:|||:|||:|.|.|:
Mosquito   238 LSYDPAAGILNVKLVEAQDLQPQDFSGTADPYAKIRLLPDRNNMWQTRIHKKTLNPVFDEDFVFE 302

  Fly   265 SLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQEKLGDI 329
             :..|....:||...:||||.:|:|..||.|:.||..:.||:.|:.||.|:....:..::.|||:
Mosquito   303 -VRSATIGRRTLEILLFDFDAYSRHVCIGGVQFPLAQVCLAERIDIWRPLLPYTEQDNKQDLGDL 366

  Fly   330 CFSLRYVPTAGKLTVVILEAKNLKKMD-VGGLSDPYVKIAIMQ-NGKRLKKKKTSIKKCTLNPYY 392
            ..||.|.|.|.||||||::|:||:.:| ....||||||:.:.. :|:||||:||::.:.|..|.|
Mosquito   367 MVSLSYQPAAEKLTVVIIKARNLRVIDGTRNSSDPYVKVCLYNADGRRLKKRKTTVARNTTAPVY 431

  Fly   393 NESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRH----WSDMLASPRRP 453
            ||:.:|::..|.::...:...|:....:|.:|.:||   ..:|:|.|.|.    :.|.|...|..
Mosquito   432 NEALTFDISRETLRDCSIEFQVLHDSLLGKNETLGR---ATVGSGPEFRQENRKFFDELFRTRAA 493

  Fly   454 IAQWHTL 460
            .|||.:|
Mosquito   494 TAQWISL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	20/98 (20%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	50/123 (41%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	54/141 (38%)
LOC1275499	XP_061516541.1	None