Protein Alignment Syt1 and rph3aa

DIOPT Version :9

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_005172658.1
• Gene: rph3aa / 101886567
• ZFINID: ZDB-GENE-090706-2
• Length: 598
• Species: Danio rerio
• Alignment Length: 497
• Identity: 150/497 - (30%)
• Similarity: 224/497 - (45%)
• Gaps: 75/497 - (15%)

  Fly     7 SETDAKPEA-EPAPASEPAADLESV-----DQKLE-ETHHSKFREVDRQEQEVLAEKAAEAASQR 64
            |.|...|.| :.:|.:....:.|||     :|::. ||..:|     |:|:.|::::|.|....|
Zfish   142 SRTSTNPSANQQSPITSQTKNAESVQVTGREQQISAETMPAK-----REERSVISQRALEEDGGR 201

  Fly    65 IAQVESTTRS-ATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFG 128
               ..||.:| |..|.|    |..||:|:     ||  .|.:.|....::....|
Zfish   202 ---HRSTVQSDAAMEGQ----TFSPVVKR-----EV--PVQSSRPPASSFSTTPI---------- 242

  Fly   129 IIFFCVRRFLKKRRTKDGKGKKGVDMKSVQLLGSAYKEKV--QPDMEELTENAEEGDEEDKQSEQ 191
                      :|......:.:....|::...|.:|.....  ||. ...||:.|:.:..|.....
Zfish   243 ----------QKDTMSRPEARAPPAMQADARLPAANSVPASRQPP-PPTTEDEEDANSYDSDDAT 296

  Fly   192 KLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLP--DKKKKFETKVHRKTLS 254
            .||.|.|.|.|....|.|...:|:|:.|..:|..|.:|||||::|||  .|..|..||..|.||:
Zfish   297 TLGMLEFSLLYTEEKNELHCNIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRTTLN 361

  Fly   255 PVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQ------TIEEWRD 313
            ||:|||..:..:...|...|||..::.|.|:|..::.|||.:|.|..:.|.|      .:|....
Zfish   362 PVWNETLVYHGITNEDMQKKTLRLSVSDEDKFGHNEFIGETRVVLKKLKLNQKKTYNVCLERVIP 426

  Fly   314 LVSVEGEGGQ---------------EKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDP 363
            :....|.|..               |:.|.|..||.|....|:|.|.::...:|..||..|.|||
Zfish   427 VRRTAGGGASRGMALYEEELKDDEAEERGRILVSLTYNSQQGRLIVGVVRCAHLAAMDSNGYSDP 491

  Fly   364 YVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGR 428
            :|||.:..:..:..|.||.|||.||||.:||.||:|:...::.|..|.|:|.|||...:::.||.
Zfish   492 FVKICLKPDMGKKAKYKTQIKKKTLNPEFNEEFSYEIKHGELAKKTLDVSVWDYDMGKSNDFIGG 556

  Fly   429 CILGCMGTGTELRHWSDMLASPRRPIAQWHTL--KDPEETDE 468
            |.||....|..|:||.:.|.:..:.|.:||.|  :...|.|:
Zfish   557 CQLGITAKGECLKHWYECLKNKDKKIERWHVLLNQSSVEADD 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Podoplanin	5..136	CDD:283467	33/136 (24%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	48/131 (37%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	54/136 (40%)
rph3aa	XP_005172658.1	PHD_SF	53..131	CDD:304600
		C2A_Rabphilin_Doc2	298..421	CDD:176000	47/122 (39%)
		C2B_Rabphilin_Doc2	456..588	CDD:176030	52/131 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000