Protein Alignment Syt1 and syt15

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_002941809.1
• Gene: syt15 / 100496499
• XenbaseID: XB-GENE-6050096
• Length: 420
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 124/427 - (29%)
• Similarity: 201/427 - (47%)
• Gaps: 77/427 - (18%)

  Fly   100 VTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCVRRF----------------------LKKRR 142
            ::|.:|...|    ||:.::.::.|:..| ::...:||                      :.|..
 Frog     1 MSEEVAAVAG----GVIGVVAILLLIGIG-VYILRKRFCFSSQYEEFFNQVPPTHTEVIAVDKDS 60

  Fly   143 TKDGKGKKGVDMKSVQL-----------LGSAYKEKVQPDMEELT-------------------- 176
            ...|...|...||.|..           :|....|::|.|.|..|
 Frog    61 MSLGTHNKDAVMKHVPFIVPPKFRGRDWIGLGNGERIQDDSEPYTAPDFLPRSSFCSLGGAYVVG 125

  Fly   177 -------ENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTS-DPYVK 233
                   :..||.:|.| ..|..:||:.|.:||:..:..|.|::::...   |..|..| :|:||
 Frog   126 SINPALYKFPEENEETD-FPEGNIGRIWFAVEYELETERLVVSLMKVRN---LQFGSDSCNPFVK 186

  Fly   234 VYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVP 298
            ::||||:::..::|..|||::|.|:|||.|: :.......:||.|:|:..|:..||..:|:|..|
 Frog   187 IHLLPDERRHLQSKTKRKTVNPQFDETFVFQ-VSGKTVHQRTLRFSIYHVDKIKKHHLLGQVVFP 250

  Fly   299 LCTIDLA--QTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGG-L 360
            |....|.  :.:..|||| .:|......:.|:|.|||.|....|:||||:|.||.|:.::..| :
 Frog   251 LKNESLTDDENVVIWRDL-ELENLEPPSEYGNIQFSLSYNDYLGRLTVVLLRAKGLQFLEERGVI 314

  Fly   361 SDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEP 425
            |..:||::.|.:.|.:|.|||:....|.||.|||:|||:|....:....|.:.|....:...|..
 Frog   315 SSAFVKVSFMNHNKLVKCKKTAAICGTANPVYNETFSFKVEHIGLDTASLSLAVYQNAQGEKSHL 379

  Fly   426 IGRCILG-CMGT-GTELRHWSDMLASPRRPIAQWHTL 460
            :||.::| .|.| |.||.||::||..|:..:.:||.|
 Frog   380 LGRVVVGPYMYTRGRELEHWNEMLNKPKDLVKRWHAL 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	15/93 (16%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	43/126 (34%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	54/138 (39%)
syt15	XP_002941809.1	TM_EGFR-like	7..32	CDD:213052	5/29 (17%)
		C2A_Synaptotagmin-15-17	149..269	CDD:176036	43/124 (35%)
		C2B_Synaptotagmin-15	279..417	CDD:176054	54/138 (39%)