Protein Alignment Syt1 and sytl5

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_012813070.1
• Gene: sytl5 / 100496000
• XenbaseID: XB-GENE-982310
• Length: 814
• Species: Xenopus tropicalis
• Alignment Length: 539
• Identity: 116/539 - (21%)
• Similarity: 204/539 - (37%)
• Gaps: 123/539 - (22%)

  Fly     1 MPPNAKSETDAKPEAEPAPASEPAADLESVDQKLEETHHSKFREVDRQEQEV------LAEKAAE 59
            |...|..:.|.:.|:.|..:......::|:|..:.............|...:      .|.:::.
 Frog   265 MISQASFKVDVRSESRPGSSLSARGSVDSLDTGVSSPKSKGNAPSSYQSSSINVIGTLPARQSSP 329

  Fly    60 AASQRIAQVESTTRSATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFL 124
            .||...|...|.:||......: |::::|......|          ||....|..:|
 Frog   330 TASMHSAASNSHSRSGVQNGTK-TSSSIPEDMSKGH----------ERRASATPSLV-------- 375

  Fly   125 VVFGIIFFCVRRFLKKRRTKD---------GKGKKGVDMKSVQL-----LGSAYKEKVQPDMEEL 175
                    ..|..|...::|.         .:.::.:.|:|:.:     ....|.:|:..|.::|
 Frog   376 --------ISRASLSSEQSKSEYDLSGHFTEENQESISMRSISVPDYLNKDPEYIDKIDEDFDDL 432

  Fly   176 --TENAEEGDEEDKQSEQKLGRLN---------------------------------FKLEYDFN 205
              :.|..:.......|::|...||                                 ..:.|.:.
 Frog   433 GPSTNLTKSMNAHTLSDRKWTHLNVPDADADTRSLTSISLYSETGDYGNLRITGEILLNINYSYK 497

  Fly   206 SNSLAVTVIQAEELPALD-MGGTSDPYVKVYLLPDKKK--KFETKVHRKTLSPVFNETFTFKSLP 267
            :.:|.|.|.....|...| ....:|||||.||||||.:  |.:||:...|..|.||||..: .:.
 Frog   498 TGALNVVVKNCRNLAVADEKKNRTDPYVKAYLLPDKSRQSKRKTKIKTNTTDPDFNETLKY-VIS 561

  Fly   268 YADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDL---VSVEGEGGQEKLGDI 329
            :.....:||...::..|||.::..:|||.:||.:.:.....:|...|   :.:..:...:..|:|
 Frog   562 HTQLETRTLQLTVWHNDRFGRNSFLGEVDIPLDSCNFENQEDECFQLQPKMDLASDVTLQYKGEI 626

  Fly   330 CFSLRY-----------------------------VPTAGKLTVVILEAKNLKKMDVGGLSDPYV 365
            ...|||                             ||:.|.:.|:|..||||..|..||.||.:|
 Frog   627 TVGLRYITPEKNLTLPLDKVAEKKSFRKSKKANVKVPSGGLVEVLIKNAKNLTAMKSGGSSDTFV 691

  Fly   366 KIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSF-EVPFEQIQKICLVVTVVDYDRIGTSEPIGRC 429
            |..::.:..:..|.||.:.|.|:||.:|.:|:| .:....:..:|:.:||...:.:.::..:|..
 Frog   692 KGYLLPDNNKSTKHKTPVVKKTVNPEWNHTFTFASLQTSDLSNVCVELTVWGKESLTSNVFLGGV 756

  Fly   430 ILGCMGTGT---ELRHWSD 445
            .||| |:|.   ::..|.|
 Frog   757 CLGC-GSGVSYGDIVDWMD 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	17/112 (15%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	41/162 (25%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	42/153 (27%)
sytl5	XP_012813070.1	PHD_SF	11..123	CDD:473978
		FYVE_Slp5	65..111	CDD:277305
		C2A_SLP-4_5	485..609	CDD:175995	37/124 (30%)
		C2B_SLP_1-2-3-4	623..801	CDD:175987	42/153 (27%)