Protein Alignment Syt1 and syt1b

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_021323234.2
• Gene: syt1b / 100034471
• ZFINID: ZDB-GENE-060503-166
• Length: 404
• Species: Danio rerio
• Alignment Length: 368
• Identity: 197/368 - (53%)
• Similarity: 254/368 - (69%)
• Gaps: 24/368 - (6%)

  Fly    48 QEQEVLAEKAAEAAS--QRIAQVESTTRSATTEAQESTTTAVPVIKKIEHVGEVVTEVIAERTGL 110
            ::...||..::..||  |:.:::..:|.|:.|.....||||..::..|.  .:.:.|:  .:..|
Zfish    27 EDDAPLAASSSSPASLAQKESKIPGSTISSPTAVHPQTTTADSLVHSIR--SKFLNEL--HKVPL 87

  Fly   111 PTWGVVAIIILVFLVVFGIIFFCV----RRFLKKRRTKDGK---GKKGVDMKSVQLLGSAYKEKV 168
            |:|...|   |.|:.||.::..|:    :...||::.|.||   .|..::|.:|:..|:  |:.|
Zfish    88 PSWATAA---LGFITVFIVLSCCLCIFRKMIFKKKKEKGGKEKNEKNDINMSNVKEEGT--KQAV 147

  Fly   169 QPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVK 233
            ....:   .:|:|.|.|.|:: ||||:|.:.|:|:|..::|.|.||:||.|.|:||.||||||||
Zfish   148 HHTTD---SDAKEEDSESKEA-QKLGKLLYTLDYNFTDSTLIVGVIRAEGLAAMDMSGTSDPYVK 208

  Fly   234 VYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVP 298
            ||||||||||||||||||||.|.|||.|||| :|||:...||||..::|||||||||.||:|::.
Zfish   209 VYLLPDKKKKFETKVHRKTLEPTFNEHFTFK-VPYAELGGKTLVMTVYDFDRFSKHDAIGDVRLQ 272

  Fly   299 LCTIDLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDP 363
            :..:|.:...||||||...|.| .||:|||||.||||||||||||||:|||||||||||||||||
Zfish   273 MNKVDFSHLTEEWRDLQKAEKE-EQERLGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDP 336

  Fly   364 YVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQ 406
            ||||.:||||||||||||:|||.|||||||||||||||.||||
Zfish   337 YVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPSEQIQ 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	28/107 (26%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	79/123 (64%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	74/81 (91%)
syt1b	XP_021323234.2	None