DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment colt and SCaMC

DIOPT Version :9

Sequence 1:	NP_477221.1	Gene:	colt / 33470	FlyBaseID:	FBgn0019830	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	82/308 - (26%)
Similarity:	134/308 - (43%)	Gaps:	37/308 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMS 81
            :..:.||..|..:.....|||.|||.||.        |....|..:|....:...|.|.:::|..
  Fly   287 RHLVAGGIAGAVSRTCTAPLDRIKVYLQV--------QTQRMGISECMHIMLNEGGSRSMWRGNG 343

  Fly    82 APLTGVAPIFAMCFAGYALGKRLQQRGEDA--KLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQ 144
            ..:..:||..|..||.|...||| .||:|.  :::..:.|.||:.:|..|..|:.|.|.:|..|.
  Fly   344 INVLKIAPETAFKFAAYEQMKRL-IRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLA 407

  Fly   145 TQQ-GQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEAL-QDVAKSKS 207
            .:: ||     |.|:.|.|.|:||:.|:||.::|....:|..||..|:...|||.| :....:..
  Fly   408 LRRTGQ-----YAGIADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIANHD 467

  Fly   208 ETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKHGIR----------------- 255
            ...|.|....:..|..:.....:...|..::::|||:....|..:..|
  Fly   468 NNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEET 532

  Fly   256 --SVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGIELANKFFNI 301
              .:|:.::.::|...||||:||..|:..||.:..:...|..::...|
  Fly   533 MTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGI 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
colt	NP_477221.1	Mito_carr	12..107	CDD:395101	26/89 (29%)
		Mito_carr	112..202	CDD:395101	31/91 (34%)
		Mito_carr	210..299	CDD:395101	21/107 (20%)
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	27/91 (30%)
		Mito_carr	375..463	CDD:278578	31/92 (34%)
		Mito_carr	470..581	CDD:278578	22/111 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441762
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840